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用于二级卒中预防的抗血小板/抗血栓治疗的优化。

Optimization of antiplatelet/antithrombotic therapy for secondary stroke prevention.

作者信息

Srivastava Padma

机构信息

Department of Neurology, CN Center, AIIMS, Ansari Nagar, New Delhi, India.

出版信息

Ann Indian Acad Neurol. 2010 Jan;13(1):6-13. doi: 10.4103/0972-2327.61270.

DOI:10.4103/0972-2327.61270
PMID:20436740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2859581/
Abstract

Role of antiplatelet therapy in secondary stroke prevention is of major significance. Antiplatelet agents predominantly in use are aspirin, clopidogrel, and combination regimes. The review focuses on the optimization of antiplatelet regimen based on evidence obtained from randomized-controlled trials, on different antiplatelet regimes and the risk assessment that may be unique to each patient.

摘要

抗血小板治疗在二级卒中预防中的作用具有重大意义。目前主要使用的抗血小板药物是阿司匹林、氯吡格雷以及联合用药方案。本综述重点关注基于随机对照试验证据的抗血小板治疗方案优化、不同的抗血小板治疗方案以及每位患者可能特有的风险评估。

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The Essen stroke risk score predicts recurrent cardiovascular events: a validation within the REduction of Atherothrombosis for Continued Health (REACH) registry.埃森中风风险评分可预测心血管事件复发:在持续健康动脉粥样硬化血栓形成减少(REACH)注册研究中的验证。
Stroke. 2009 Feb;40(2):350-4. doi: 10.1161/STROKEAHA.108.521419. Epub 2008 Nov 20.
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Antiplatelet drugs in cardiological practice: established strategies and new developments.心脏病学实践中的抗血小板药物:既定策略与新进展
Vasc Health Risk Manag. 2008;4(3):637-45. doi: 10.2147/vhrm.s2691.
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Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study.在有效避免二次中风预防方案(PRoFESS)试验中,阿司匹林加缓释双嘧达莫与氯吡格雷及替米沙坦对缺血性中风患者复发性中风后残疾和认知功能的影响:一项双盲、活性药物与安慰剂对照研究。
Lancet Neurol. 2008 Oct;7(10):875-84. doi: 10.1016/S1474-4422(08)70198-4. Epub 2008 Aug 29.
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