Division of Hematology, Oncology, and Blood and Marrow Transplantation, University of Iowa and Iowa City Veterans' Administration Medical Center, Iowa City, IA, USA.
Curr Oncol Rep. 2010 Jul;12(4):247-52. doi: 10.1007/s11912-010-0103-6.
Currently, 10% of cancer chemotherapy is prescribed to patients by means of an oral formulation, but, by 2013, this percentage is predicted to increase to 25%. Oral chemotherapy offers many advantages, including no need for sometimes painful intravenous access, no intravenous drug administration fees, more time at home for patients, and a greater sense of patient autonomy. However, oral cancer chemotherapy also poses challenges, many of which revolve around adherence and safety. These challenges are discussed here. There are few other circumstances in which patient education and the maintenance of institutional safety infrastructure play such an integral role in sustaining favorable cancer clinical outcomes.
目前,有 10%的癌症化疗是通过口服制剂开给患者的,但到 2013 年,这一比例预计将增加到 25%。口服化疗有许多优点,包括无需有时会引起疼痛的静脉通路,无需静脉药物管理费用,患者在家的时间更多,以及更大的患者自主性。然而,口服癌症化疗也带来了挑战,其中许多挑战都围绕着依从性和安全性。本文讨论了这些挑战。在其他情况下,患者教育和维护机构安全基础设施在维持有利的癌症临床结果方面发挥着如此重要的作用。