Department of Obstetrics and Gynecology, Erasmus University Medical Center, SK 4130, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Eur J Epidemiol. 2010 Jun;25(6):421-9. doi: 10.1007/s10654-010-9458-0. Epub 2010 May 1.
The potential relationship between daily physical activity and pregnancy outcome remains unclear because of the wide variation in study designs and physical activity assessment measures. We sought to prospectively quantify the potential effects of the various domains of physical activity on selected birth outcomes in a large unselected population. The sample consisted of 11,759 singleton pregnancies from the Avon longitudinal study of parents and children, United Kingdom. Information on daily physical activity was collected by postal questionnaire for self-report measures. Main outcome measures were birth weight, gestational age at delivery, preterm birth and survival. After controlling for confounders, a sedentary lifestyle and paid work during the second trimester of pregnancy were found to be associated with a lower birth weight, while 'bending and stooping' and 'working night shifts' were associated with a higher birth weight. There was no association between physical exertion and duration of gestation or survival. Repetitive boring tasks during the first trimester was weakly associated with an increased risk of preterm birth (<37 weeks) (adjusted odds ratio [OR] = 1.25, 95% CI 1.04-1.50). 'Bending and stooping' during the third trimester was associated with a reduced risk of preterm birth (adjusted OR = 0.73, 95% CI 0.63-0.84). Demanding physical activities do not have a harmful effect on the selected birth outcomes while a sedentary lifestyle is associated with a lower birth weight. In the absence of either medical or obstetric complications, pregnant women may safely continue their normal daily physical activities should they wish to do so.
由于研究设计和体力活动评估措施的广泛差异，每日体力活动与妊娠结局之间的潜在关系仍不清楚。我们旨在前瞻性地量化各种体力活动领域对大量未选择人群中特定出生结局的潜在影响。该样本由英国阿冯纵向父母和儿童研究中的 11759 例单胎妊娠组成。通过邮寄问卷进行自我报告措施来收集每日体力活动信息。主要结局指标是出生体重、分娩时的胎龄、早产和存活率。在控制混杂因素后，发现妊娠中期久坐不动的生活方式和有薪工作与较低的出生体重相关，而“弯腰和蹲下”和“上夜班”与较高的出生体重相关。体力活动与妊娠持续时间或存活率之间没有关联。妊娠早期的重复无聊任务与早产风险增加（<37 周）（调整后的优势比[OR] = 1.25，95%可信区间 1.04-1.50）相关。妊娠晚期“弯腰和蹲下”与早产风险降低相关（调整后的 OR = 0.73，95%可信区间 0.63-0.84）。需要体力活动不会对所选出生结局产生有害影响，而久坐不动的生活方式与较低的出生体重相关。在没有医学或产科并发症的情况下，如果孕妇愿意，她们可以安全地继续进行正常的日常体力活动。
