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常年性鼻过敏患者下鼻甲氩等离子体凝固术的24个月随访研究

A 24-month-follow-up study of argon plasma coagulation of the inferior turbinate in patients with perennial nasal allergy.

作者信息

Iwasaki Akemi, Tokano Hisashi, Kamiyama Ryosuke, Suzuki Yasuhiro, Kitamura Ken

机构信息

Department of Otolaryngology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

J Med Dent Sci. 2010 Mar;57(1):11-5.

PMID:20437761
Abstract

We report a 24-month-follow-up study of argon plasma coagulation of the inferior turbinate (APC) in patients with perennial nasal allergy. This was a retrospective study, in which 41 patients with perennial allergic rhinitis were treated by inferior turbinate reduction using APC. The grades of nasal stuffiness, rhinorrhea, sneezing and the daily activity impairment caused by these nasal symptoms were evaluated before and then 6, 9, 12, 15, 18, 21, and 24 months after APC, using a questionnaire graded on a four-point scale according to the Severity Criteria of Symptoms of Nasal Allergy issued by the Japanese Society of Allergology. Both nasal stuffiness and any daily activity impairment significantly improved 6 months after APC. Twenty four months after APC, 8/10 (80%) of the patients reported mild or no stuffiness and 9/10 (90%) of the patients reported mild or no daily activity impairement. Neither rhinorrhea nor sneezing were significantly improved during this study. Of the 41 patients 18 (43.9%) received no additional treatment. A second APC treatment was administered to 10/41 (24.4%) patients during follow-up period. Additional conservative medications were needed in 15/41 (36.6%) patients. Among the patients uncontrolled by conservative medical treatment, inferior turbinate reduction using APC provides significant relief in a 24-month-follow-up from nasal stuffiness and daily activity impairment.

摘要

我们报告了一项针对常年性鼻过敏患者下鼻甲氩等离子体凝固术(APC)的24个月随访研究。这是一项回顾性研究,其中41例常年性变应性鼻炎患者接受了APC下鼻甲缩小治疗。在APC治疗前以及治疗后6、9、12、15、18、21和24个月,使用根据日本变态反应学会发布的鼻过敏症状严重程度标准制定的四分制问卷,对鼻塞、流涕、打喷嚏的程度以及这些鼻部症状导致的日常活动受限情况进行评估。APC治疗6个月后,鼻塞和日常活动受限情况均有显著改善。APC治疗24个月后,8/10(80%)的患者报告鼻塞轻微或无鼻塞,9/10(90%)的患者报告日常活动受限轻微或无受限。在本研究期间,流涕和打喷嚏均未得到显著改善。41例患者中,18例(43.9%)未接受额外治疗。在随访期间,10/41(24.4%)的患者接受了第二次APC治疗。15/41(36.6%)的患者需要额外的保守药物治疗。在保守药物治疗无法控制的患者中,APC下鼻甲缩小术在24个月的随访中能显著缓解鼻塞和日常活动受限情况。

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