Department of Medicine 3, Medical University of Vienna, Vienna, Austria.
Gastrointest Endosc. 2010 May;71(6):1052-5. doi: 10.1016/j.gie.2009.12.059.
Megachannel is a newly developed colonic access system allowing rapid and multiple passes of the colonoscope to the right side of the colon.
The aim of this study was to evaluate the safety and clinical feasibility of placing a 100 cm Megachannel prototype in the right side of the colon.
Six centers, international, both surgeons and gastroenterologists performing endoscopy.
Patients scheduled for colonoscopy with suspected right-side colonic polypoid lesions were included. The prototype was loaded onto a 160 cm lower GI endoscope and introduced via colonoscopic guidance.
The ability to place this device in the right side of the colon.
The Megachannel prototype was introduced in 41 patients (19 female, mean age 54 years) undergoing colonoscopy. The cecum was reached in 27 cases (66%) within 18 minutes (range, 3-35 minutes) and with 73 cm (range, 40-100 cm) of the device being inserted into the colon. Mild tissue bruises and mild pain were observed in 5 and 3 patients, respectively. In 14 patients, the device assisted the removal of multiple polyps (2-12) as tissue was repeatedly retrieved through the channel. The device also allowed delivery of an endoscopic US scope or suction caps to the right side of the colon.
Prototype performance may differ from the actual product (80 cm in length, redesigned introducer plugs). Small number of patients, difficult in diverticular disease.
This newly developed colonic access system can be safely placed in the right side of the colon and is useful for a variety of advanced procedures that require repeated insertion of the colonoscope or delivery of bulky instruments. (
NCT00987896.).
Megachannel 是一种新开发的结肠进入系统，可允许结肠镜快速且多次进入结肠右侧。
本研究旨在评估将 100cm Megachannel 原型置于结肠右侧的安全性和临床可行性。
六个国际中心，由进行内镜检查的外科医生和胃肠病学家共同参与。
纳入计划接受结肠镜检查且疑似右侧结肠息肉样病变的患者。该原型被加载到 160cm 下胃肠道内镜上，并通过结肠镜引导进行引入。
将该设备置于结肠右侧的能力。
在 41 例接受结肠镜检查的患者（19 例女性，平均年龄 54 岁）中引入了 Megachannel 原型。在 18 分钟内（范围 3-35 分钟），有 27 例（66%）到达盲肠，且有 73cm（范围 40-100cm）的设备插入结肠。有 5 例患者观察到轻微的组织瘀伤，3 例患者观察到轻微疼痛。在 14 例患者中，该设备辅助移除了多个息肉（2-12 个），因为组织通过通道反复被取出。该设备还允许将内镜超声探头或吸引帽输送到结肠右侧。
原型性能可能与实际产品不同（长度为 80cm，重新设计的引入器塞）。患者数量较少，在憩室疾病中较难应用。
这种新开发的结肠进入系统可以安全地置于结肠右侧，并且对于需要反复插入结肠镜或输送大型仪器的各种先进操作非常有用。（临床试验注册号：NCT00987896.）。
