Delbarre G, Delbarre B, Ferger A, Calinon F
Laboratoire de Recherches Physiopathologiques, Faculté de Médecine, Tours, France.
Brain Inj. 1991 Jan-Mar;5(1):87-91. doi: 10.3109/02699059108998517.
This study examined brain-stem auditory evoked potentials response (BAEP) changes in the gerbil after temporary occlusion of the left carotid artery. Fourteen adult gerbils were subjected to unilateral left carotid ligation for 30 min. BAEPs were registered before and 5 min after occlusion, then 5 min, 60 min, 120 min, 24 h, 7 days and 28 days after release of the clip. Waves I (cochlear nerve), III (superior olivary complex) and V (inferior colliculus) were examined. Results were analysed using paired Student's t-test. Transient ischaemia increased latencies of waves I, III and V and the changes were more severe 5 min after release of the clip. In the gerbil, BAEPs might be a suitable method to study cerebral ischaemia.
本研究检测了沙土鼠在左颈动脉暂时闭塞后脑干听觉诱发电位反应（BAEP）的变化。14只成年沙土鼠接受了左侧颈动脉单侧结扎30分钟。在闭塞前和闭塞后5分钟记录BAEP，然后在松开夹子后5分钟、60分钟、120分钟、24小时、7天和28天记录。检测了I波（蜗神经）、III波（上橄榄复合体）和V波（下丘）。结果采用配对学生t检验进行分析。短暂性缺血增加了I波、III波和V波的潜伏期，且在松开夹子后5分钟变化更为严重。在沙土鼠中，BAEP可能是研究脑缺血的一种合适方法。
