School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Brazil.
J Med Ethics. 2010 Jun;36(6):344-8. doi: 10.1136/jme.2009.035113. Epub 2010 May 3.
To evaluate the modes of death and treatment offered in the last 24 h of life to patients dying in 10 Brazilian intensive care units (ICUs) over a period of 2 years.
Cross-sectional, multicentre, retrospective study based on medical chart review. The medical records of all patients that died in seven paediatric and three adult ICUs belonging to university and tertiary hospitals over a period of 2 years were included. Deaths in the first 24 h of admission to the ICU and brain death were excluded.
Two intensive care fellows of each ICU were trained in fulfilling a standard protocol (kappa=0.9) to record demographic data and all medical management provided in the last 48 h of life. The Student t test, Mann-Whitney U test, chi(2) test and RR were used for data comparison.
1053 medical charts were included (59.4% adult patients). Life support limitation was more frequent in the adult group (86% vs 43.5%; p<0.001). A 'do not resuscitate' order was the most common life support limitation in both groups (75% and 66%), whereas withholding/withdrawing were more frequent in the paediatric group (33.9% vs 24.9%; p=0.02). The life support limitation was rarely reported in the medical chart in both groups (52.6% and 33.7%) with scarce family involvement in the decision making process (23.0% vs 8.7%; p<0.001).
Life support limitation decision making in Brazilian ICUs is predominantly centred on the medical perspective with scarce participation of the family, and consequently several non-coherent medical interventions are observed in patients with life support limitation.
评估在 2 年内,10 家巴西重症监护病房(ICU)中 24 小时内死亡的患者的死亡模式和临终治疗方式。
基于病历回顾的横断面、多中心、回顾性研究。纳入了两所大学和一家三级医院的 7 家儿科和 3 家成人 ICU 中在 2 年内死亡的所有患者的病历。排除 ICU 入住后 24 小时内死亡和脑死亡的患者。
每个 ICU 的 2 名重症监护医生接受培训,以填写标准协议(kappa=0.9),记录人口统计学数据和生命末期 48 小时内的所有医疗管理。使用学生 t 检验、Mann-Whitney U 检验、卡方检验和相对危险度(RR)进行数据比较。
共纳入 1053 份病历(59.4%为成人患者)。生命支持限制在成人组更为常见(86%比 43.5%;p<0.001)。两组中最常见的生命支持限制是“不复苏”医嘱(75%和 66%),而儿科组更常见的是 withholding/withdrawing(33.9%比 24.9%;p=0.02)。两组的病历中很少报告生命支持限制(52.6%和 33.7%),且家庭在决策过程中的参与度低(23.0%比 8.7%;p<0.001)。
巴西 ICU 中的生命支持限制决策主要以医疗观点为中心,家庭参与度低,因此在有生命支持限制的患者中观察到了几种不协调的医疗干预措施。