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[喀麦隆雅温得一家儿科中心重症监护病房收治的3至59个月儿童的死亡率模式]

[Mortality pattern in children aged 3-59 months hospitalized in the Intensive Care Unit at a Paediatric Center in Yaounde-Cameroon].

作者信息

Nguefack Félicitée, Mah Evelyn, Kinkela Mina Ntoto, Tagne Thierry, Chelo David, Dongmo Roger, Ndombo Paul Koki

机构信息

Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun.

Hôpital Gynéco-obstétrique et Pédiatrique de Yaoundé, Yaoundé, Cameroun.

出版信息

Pan Afr Med J. 2020 Aug 5;36:246. doi: 10.11604/pamj.2020.36.246.11292. eCollection 2020.

Abstract

INTRODUCTION

mortality risk is high at the Intensive Care Units (ICU) in developing countries. We here report the deaths occurred in the ICU at the Mother and Child Center in Yaounde, Cameroon.

METHODS

we conducted a retrospective study on the clinical, socio-demographic features, the therapeutic strategy as well as some of the factors associated with deaths occurred in 200 patients aged 3-59 months between 2010 and 2014.

RESULTS

out of 2675 patients included in the study, 1807 were aged 3-59 months and 303 died. The overall and cause-specific mortality rate in this age group was 11.3% and 16.7% respectively. Most patients (152/200; 76.0%) died within 24 months and the median admission time was 7 days. More than half of patients (57.0%) presented to a health center and only 66 (33.0%) presented to a referral hospital. Severe malaria (41.5%), pneumonia (22.7%) and gastroenteritis (27.8%) were the most common diseases. Malnutrition and HIV/AIDS were the underlying causes of death in 23.0% and 20.5% of patients respectively. Gastroenteritis multiplied the risk of death of approximately 6 times (OR = 5.76; p = 0.000) in patients affected by malnutrition and HIV infection. Deaths mainly occurred (90.0%) within 72 hours of admission.

CONCLUSION

despite limited resources, some diseases could have been easily treated avoiding complications which require reanimation. It is essential to intensify the fight against malaria, HIV infection and malnutrition.

摘要

引言

在发展中国家,重症监护病房(ICU)的死亡率很高。我们在此报告喀麦隆雅温得母婴中心ICU发生的死亡情况。

方法

我们对2010年至2014年间年龄在3至59个月的200例患者的临床、社会人口学特征、治疗策略以及与死亡相关的一些因素进行了回顾性研究。

结果

在纳入研究的2675例患者中,1807例年龄在3至59个月,303例死亡。该年龄组的总体死亡率和特定病因死亡率分别为11.3%和16.7%。大多数患者(152/200;76.0%)在24个月内死亡,中位住院时间为7天。超过一半的患者(57.0%)前往健康中心就诊,只有66例(33.0%)前往转诊医院就诊。重症疟疾(41.5%)、肺炎(22.7%)和胃肠炎(27.8%)是最常见的疾病。营养不良和艾滋病毒/艾滋病分别是23.0%和20.5%患者的潜在死亡原因。在受营养不良和艾滋病毒感染影响的患者中,胃肠炎使死亡风险增加约6倍(OR = 5.76;p = 0.000)。死亡主要发生在入院72小时内(90.0%)。

结论

尽管资源有限,但一些疾病本可轻松治疗,避免出现需要复苏的并发症。加强抗击疟疾、艾滋病毒感染和营养不良至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/908b/7519789/beea170bd4ad/PAMJ-36-246-g001.jpg

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