• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency.双敏感胶束纳米颗粒调节DNA解包并提高基因传递效率。
Adv Mater. 2010 Jun 18;22(23):2556-60. doi: 10.1002/adma.200903933.
2
Virus-sized DNA nanoparticles for gene delivery based on micelles of cationic calixarenes.基于阳离子杯芳烃胶束的病毒大小 DNA 纳米颗粒用于基因传递。
Chemistry. 2011 May 9;17(20):5526-38. doi: 10.1002/chem.201100154. Epub 2011 Apr 18.
3
A small library of DNA-encapsulated supramolecular nanoparticles for targeted gene delivery.用于靶向基因传递的 DNA 封装超分子纳米粒子的小型文库。
Chem Commun (Camb). 2010 Mar 21;46(11):1851-3. doi: 10.1039/b923711a. Epub 2010 Feb 11.
4
Probing in vivo trafficking of polymer/DNA micellar nanoparticles using SPECT/CT imaging.利用 SPECT/CT 成像探测聚合物/DNA 胶束纳米粒的体内转运。
Mol Ther. 2011 Sep;19(9):1626-35. doi: 10.1038/mt.2011.128. Epub 2011 Jul 12.
5
Au nanoinjectors for electrotriggered gene delivery into the cell nucleus.用于电触发基因递送至细胞核的金纳米注射器。
Methods Mol Biol. 2015;1228:55-65. doi: 10.1007/978-1-4939-1680-1_6.
6
String-like micellar nanoparticles formed by complexation of PEG-b-PPA and plasmid DNA and their transfection efficiency.由 PEG-b-PPA 与质粒 DNA 络合形成的类似链状的胶束纳米粒及其转染效率。
Pharm Res. 2011 Jun;28(6):1317-27. doi: 10.1007/s11095-011-0436-3. Epub 2011 Apr 16.
7
Nuclear inclusion of nontargeted and chromatin-targeted polystyrene beads and plasmid DNA containing nanoparticles.非靶向和染色质靶向聚苯乙烯珠核及含纳米颗粒的质粒 DNA 的核内包含物。
Mol Pharm. 2011 Oct 3;8(5):1757-66. doi: 10.1021/mp200120v. Epub 2011 Aug 22.
8
Programmed assembly of polymer-DNA conjugate nanoparticles with optical readout and sequence-specific activation of biorecognition.具有光学读出和生物识别序列特异性激活功能的聚合物 - DNA 共轭纳米颗粒的程序化组装
Nanoscale. 2014 Feb 21;6(4):2368-74. doi: 10.1039/c3nr04952c. Epub 2013 Nov 22.
9
Nuclease-resistant DNA via high-density packing in polymeric micellar nanoparticle coronas.通过在聚合物胶束纳米颗粒冠层中高密度堆积实现耐核酸酶 DNA
ACS Nano. 2013 Feb 26;7(2):1379-87. doi: 10.1021/nn305030g. Epub 2013 Feb 4.
10
Hydroxyapatite nanoparticles as vectors for gene delivery.羟基磷灰石纳米颗粒作为基因递送载体
Ther Deliv. 2012 May;3(5):623-32. doi: 10.4155/tde.12.39.

引用本文的文献

1
Dual targeting nanoparticles for epilepsy therapy.用于癫痫治疗的双靶向纳米颗粒。
Chem Sci. 2022 Oct 19;13(43):12913-12920. doi: 10.1039/d2sc03298h. eCollection 2022 Nov 9.
2
Native Chemical Ligation for Cross-Linking of Flower-Like Micelles.用于交联花状胶束的天然化学连接。
Biomacromolecules. 2018 Sep 10;19(9):3766-3775. doi: 10.1021/acs.biomac.8b00908. Epub 2018 Aug 24.
3
Self-assembly of pH-sensitive fluorinated peptide dendron functionalized dextran nanoparticles for on-demand intracellular drug delivery.用于按需细胞内药物递送的pH敏感型氟化肽树枝状大分子功能化葡聚糖纳米颗粒的自组装。
J Mater Sci Mater Med. 2015 Aug;26(8):219. doi: 10.1007/s10856-015-5550-z. Epub 2015 Aug 4.
4
Shape Control in Engineering of Polymeric Nanoparticles for Therapeutic Delivery.用于治疗递送的聚合物纳米颗粒工程中的形状控制
Biomater Sci. 2015 Jul;3(7):894-907. doi: 10.1039/C5BM00006H.
5
Bioorthogonal Oxime Ligation Mediated Cancer Targeting.生物正交肟连接介导的癌症靶向
Chem Sci. 2015 Apr 1;6(4):2182-2186. doi: 10.1039/C5SC00063G.
6
Enhanced Non-Viral Gene Delivery to Human Embryonic Stem Cells via Small Molecule-Mediated Transient Alteration of Cell Structure.通过小分子介导的细胞结构瞬时改变增强非病毒基因向人胚胎干细胞的递送
J Mater Chem B. 2014;2(46):8098-8105. doi: 10.1039/C4TB00750F.
7
Core-Crosslinked Polymeric Micelles: Principles, Preparation, Biomedical Applications and Clinical Translation.核交联聚合物胶束：原理、制备、生物医学应用及临床转化
Nano Today. 2015 Feb 1;10(1):93-117. doi: 10.1016/j.nantod.2015.01.005.
8
Three-dimensional hydrodynamic focusing method for polyplex synthesis.三维流聚焦法合成多聚物。
ACS Nano. 2014 Jan 28;8(1):332-9. doi: 10.1021/nn404193e. Epub 2014 Jan 10.
9
Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cells.基于阳离子螺旋多肽的基因传递用于IMR-90成纤维细胞和人类胚胎干细胞
Biomater Sci. 2013 Jul;1(7):719-727. doi: 10.1039/C3BM00006K.
10
Light-responsive helical polypeptides capable of reducing toxicity and unpacking DNA: toward nonviral gene delivery.能够降低毒性并解开DNA的光响应性螺旋多肽：迈向非病毒基因递送
Angew Chem Int Ed Engl. 2013 Aug 26;52(35):9182-9186. doi: 10.1002/anie.201302820. Epub 2013 Jul 5.

本文引用的文献

1
Delivery of nucleic acids via disulfide-based carrier systems.基于二硫键的载体系统递呈核酸。
Adv Mater. 2009 Sep 4;21(32-33):3286-306. doi: 10.1002/adma.200802453.
2
Simultaneous Non-invasive Analysis of DNA Condensation and Stability by Two-step QD-FRET.通过两步量子点荧光共振能量转移对DNA凝聚和稳定性进行同步无创分析。
Nano Today. 2009 Apr 1;4(2):125-134. doi: 10.1016/j.nantod.2009.02.008.
3
Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET.通过基于量子点-荧光共振能量转移构建的模型对多聚体的细胞内解包动力学进行定量比较。
Mol Ther. 2008 Feb;16(2):324-32. doi: 10.1038/sj.mt.6300392. Epub 2008 Jan 8.
4
PEG-b-PPA/DNA micelles improve transgene expression in rat liver through intrabiliary infusion.聚乙二醇-嵌段-聚丙烯酸/DNA胶束通过胆管内输注提高大鼠肝脏中的转基因表达。
J Control Release. 2007 Oct 8;122(3):297-304. doi: 10.1016/j.jconrel.2007.06.014. Epub 2007 Jun 22.
5
Crosslinked nanocarriers based upon poly(ethylene imine) for systemic plasmid delivery: in vitro characterization and in vivo studies in mice.基于聚乙烯亚胺的交联纳米载体用于全身质粒递送：体外表征及小鼠体内研究
J Control Release. 2007 Apr 23;118(3):370-80. doi: 10.1016/j.jconrel.2007.01.007. Epub 2007 Jan 20.
6
Polyplex gene delivery modulated by redox potential gradients.由氧化还原电位梯度调节的多聚体基因递送
J Drug Target. 2006 Sep;14(8):519-26. doi: 10.1080/10611860600834409.
7
Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression.具有可控电荷密度和二硫键交联的块状阳离子聚合物复合物，旨在增强基因表达。
J Am Chem Soc. 2004 Mar 3;126(8):2355-61. doi: 10.1021/ja0379666.
8
Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo.体内具有延长全身循环时间的二硫键交联聚电解质基因递送复合物的触发式细胞内激活。
Gene Ther. 2001 May;8(9):713-24. doi: 10.1038/sj.gt.3301446.
9
Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency.壳聚糖-脱氧核糖核酸纳米颗粒作为基因载体：合成、表征及转染效率
J Control Release. 2001 Feb 23;70(3):399-421. doi: 10.1016/s0168-3659(00)00361-8.
10
A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization.溴化乙锭与核酸之间的荧光复合物。物理化学特性
J Mol Biol. 1967 Jul 14;27(1):87-106. doi: 10.1016/0022-2836(67)90353-1.

Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency.

作者信息

Jiang Xuan, Zheng Yiran, Chen Hunter H, Leong Kam W, Wang Tza-Huei, Mao Hai-Quan

机构信息

Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

出版信息

Adv Mater. 2010 Jun 18;22(23):2556-60. doi: 10.1002/adma.200903933.

DOI:10.1002/adma.200903933
PMID:20440698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3000804/
Abstract
摘要