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用于靶向基因传递的 DNA 封装超分子纳米粒子的小型文库。

A small library of DNA-encapsulated supramolecular nanoparticles for targeted gene delivery.

机构信息

Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging (CIMI), University of California, Los Angeles, 570 Westwood Plazas, CNSI Building, Los Angeles, CA 90095-1770, USA.

出版信息

Chem Commun (Camb). 2010 Mar 21;46(11):1851-3. doi: 10.1039/b923711a. Epub 2010 Feb 11.

DOI:10.1039/b923711a
PMID:20198230
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2879880/
Abstract

We demonstrated a convenient, flexible and modular synthetic approach for preparation of a small library of DNA-encapsulated supramolecular nanoparticles SNPs superset DNA and RGD-SNPs superset DNA with different sizes and RGD target ligand coverage for targeted gene delivery.

摘要

我们展示了一种方便、灵活和模块化的合成方法，用于制备一小部分 DNA 封装的超分子纳米颗粒 SNP superset DNA 和 RGD-SNPs superset DNA，它们具有不同的大小和 RGD 靶向配体覆盖率，用于靶向基因递送。

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