用于靶向基因传递的 DNA 封装超分子纳米粒子的小型文库。
A small library of DNA-encapsulated supramolecular nanoparticles for targeted gene delivery.
机构信息
Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging (CIMI), University of California, Los Angeles, 570 Westwood Plazas, CNSI Building, Los Angeles, CA 90095-1770, USA.
出版信息
Chem Commun (Camb). 2010 Mar 21;46(11):1851-3. doi: 10.1039/b923711a. Epub 2010 Feb 11.
Abstract
We demonstrated a convenient, flexible and modular synthetic approach for preparation of a small library of DNA-encapsulated supramolecular nanoparticles SNPs superset DNA and RGD-SNPs superset DNA with different sizes and RGD target ligand coverage for targeted gene delivery.
摘要
我们展示了一种方便、灵活和模块化的合成方法，用于制备一小部分 DNA 封装的超分子纳米颗粒 SNP superset DNA 和 RGD-SNPs superset DNA，它们具有不同的大小和 RGD 靶向配体覆盖率，用于靶向基因递送。
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Chem Commun (Camb). 2009 Sep 28(36):5433-5. doi: 10.1039/b907283g. Epub 2009 Aug 3.
3
An integrated microfluidic device for large-scale in situ click chemistry screening.一种用于大规模原位点击化学筛选的集成微流控装置。
Lab Chip. 2009 Aug 21;9(16):2281-5. doi: 10.1039/b907430a. Epub 2009 Jun 17.
4
Construction, DNA wrapping and cleavage of a carbon nanotube-polypseudorotaxane conjugate.碳纳米管-聚准轮烷共轭物的构建、DNA包裹及切割
Chem Commun (Camb). 2009 Jul 21(27):4106-8. doi: 10.1039/b906794a. Epub 2009 Jun 8.
5
A supramolecular approach for preparation of size-controlled nanoparticles.一种用于制备尺寸可控纳米颗粒的超分子方法。
Angew Chem Int Ed Engl. 2009;48(24):4344-8. doi: 10.1002/anie.200900063.
6
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Nat Mater. 2009 Jun;8(6):526-33. doi: 10.1038/nmat2444. Epub 2009 May 3.
7
Bioresponsive polymers for nonviral gene delivery.用于非病毒基因递送的生物响应性聚合物
Curr Opin Mol Ther. 2009 Apr;11(2):165-78.
8
Engineering clustered ligand binding into nonviral vectors: alphavbeta3 targeting as an example.将成簇配体结合工程化到非病毒载体中：以αvβ3靶向为例。
Mol Ther. 2009 May;17(5):828-36. doi: 10.1038/mt.2009.11. Epub 2009 Feb 24.
9
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Biomaterials. 2009 Feb;30(5):928-38. doi: 10.1016/j.biomaterials.2008.09.067. Epub 2008 Nov 22.
10
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Chem Commun (Camb). 2008 Oct 28(40):5004-6. doi: 10.1039/b807837h. Epub 2008 Aug 18.
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