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非处方护肤品导致的新生儿化学物质暴露。

Newborn chemical exposure from over-the-counter skin care products.

作者信息

Cetta F, Lambert G H, Ros S P

机构信息

Department of Internal Medicine, Loyola University Medical Center, Maywood, IL 60153.

出版信息

Clin Pediatr (Phila). 1991 May;30(5):286-9. doi: 10.1177/000992289103000504.

Abstract

Human exposure to potentially toxic environmental chemicals is a major concern to our society. Over-the-counter (OTC) skin care products are a potential source of environmental chemical exposure to newborns. A prospective study was undertaken to define existing newborn bathing practices and quantitate environmental chemical exposure from OTC skin care products. One hundred-ninety six mothers of infants discharged from our newborn nursery were asked to respond to a questionnaire concerning newborn bathing practices and OTC skin care product usage. Complete questionnaires were returned by 23% of the mothers. The average newborn had 8 +/- 3 (+/- SEM) skin care products applied with the resultant exposure to 48 +/- 18 different environmental chemicals. Forty-seven percent of our respondents used a baby powder. The average one month old was bathed 4 times a week and was shampooed 3 times weekly. Seventy-eight percent of the respondents reported that their newborn had a rash but only 45% of those reporting a rash sought professional medical advice. Thirty-seven percent of the mothers reporting a rash made a change in bathing practice or product selection. In view of our findings, the human newborn is exposed to a large number of environmental chemicals thorough topical OTC preparations. The efficacy, transcutaneous absorption and potential toxicity of these products should be investigated.

摘要

人类接触潜在有毒环境化学物质是我们社会主要关注的问题。非处方(OTC)护肤品是新生儿接触环境化学物质的一个潜在来源。开展了一项前瞻性研究来确定现有的新生儿沐浴习惯,并对非处方护肤品导致的环境化学物质接触进行定量。我们新生儿病房出院的196名婴儿的母亲被要求回答一份关于新生儿沐浴习惯和非处方护肤品使用情况的问卷。23%的母亲返回了完整问卷。平均每个新生儿使用8±3(±标准误)种护肤品,由此接触到48±18种不同的环境化学物质。47%的受访者使用婴儿爽身粉。平均一个月大的婴儿每周洗澡4次,每周洗头3次。78%的受访者报告他们的新生儿出疹,但出疹者中只有45%寻求专业医疗建议。报告新生儿出疹的母亲中有37%改变了沐浴习惯或产品选择。鉴于我们的研究结果,人类新生儿通过局部非处方制剂接触大量环境化学物质。这些产品的功效、经皮吸收和潜在毒性应该进行研究。

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