Ishimi Yoshiko
Program for Food Function and Labeling, National Institute of Health and Nutrition.
Clin Calcium. 2010 May;20(5):762-7.
Magnesium is related to a number of biological enzymatic reactions such as catalytic role for the reaction of kinases in ATP production. On the other hand, magnesium is one of the essential minerals for bone formation. In the magnesium-deficient rats, apparent bone loss caused by increase in bone resorption and decrease in bone formation was observed. Although, epidemiological studies suggest that magnesium deficiency is one of the risk factor for osteoporosis, a relationship between magnesium intake and bone mineral density is not clear. This may be due to the differences in the population, decrease in sex hormone secretion, and the possibility that magnesium-deficiency is also accompanied with another nutrient insufficiency, e.g., calcium.
镁与许多生物酶促反应相关，比如在ATP生成过程中对激酶反应起催化作用。另一方面，镁是骨形成所必需的矿物质之一。在缺镁大鼠中，观察到由于骨吸收增加和骨形成减少导致明显的骨质流失。尽管流行病学研究表明镁缺乏是骨质疏松症的危险因素之一，但镁摄入量与骨矿物质密度之间的关系尚不清楚。这可能是由于人群差异、性激素分泌减少，以及镁缺乏可能还伴有其他营养素不足（如钙）的可能性。
