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心理困扰在喉咽反流患者中的作用:一项前瞻性问卷调查研究。

The role of psychological distress in laryngopharyngeal reflux patients: a prospective questionnaire study.

机构信息

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University, Seongdong-gu, Seoul 133-792, Korea.

出版信息

Clin Otolaryngol. 2010 Feb;35(1):25-30. doi: 10.1111/j.1749-4486.2009.02072.x.

Abstract

OBJECTIVES

To determine the role of psychological distress in laryngopharyngeal reflux patients and evaluate the correlation between symptoms, laryngeal signs, pH monitoring results and psychological profile.

DESIGN

Prospective study.

SETTING

Hanyang University Hospital, a university teaching hospital and tertiary referral center.

PARTICIPANTS

One hundred and six patients who were diagnosed with laryngopharyngeal reflux by 24-h ambulatory double probe pH monitoring and 119 healthy controls visiting our health promotion center from January 2006 to June 2007.

MAIN OUTCOME MEASURES

The psychological profile of laryngopharyngeal reflux patients measured by the Symptom Checklist-90-Revised questionnaire were evaluated and compared with those of healthy controls. The correlation between reflux symptom index, reflux finding score, parameters of pH monitoring and the Symptom Checklist-90-Revised profiles were also evaluated.

RESULTS

On the Symptom Checklist-90-Revised questionnaire, the total mean T-scores of the nine symptom dimensions and three global indices of the laryngopharyngeal reflux patients were all below 50. The Global Severity Index, which indicates overall psychological distress, was normal in all of the patients. On comparison with the control group, no statistically significant difference was noted in the psychological profile except on the Somatisation scale where laryngopharyngeal reflux patients showed significantly higher scores. Reflux symptom index showed significant positive correlation with the number of reflux episodes, percentage of time which pH fell below 4 in total positions, and DeMeester score of the upper probe. The nine symptom dimensions and three global indices of Symptom Checklist-90-Revised questionnaire did not show any correlation with reflux symptom index, reflux finding score and the parameters of the 24-h ambulatory double probe pH monitoring.

CONCLUSIONS

Laryngopharyngeal reflux patients did not demonstrate any significant level of psychological distress and their symptom severity showed significant positive correlation with reflux severity.

摘要

目的

确定心理困扰在咽喉反流患者中的作用,并评估症状、喉部体征、pH 监测结果和心理特征之间的相关性。

设计

前瞻性研究。

地点

汉阳大学医院,一所大学教学医院和三级转诊中心。

参与者

2006 年 1 月至 2007 年 6 月期间,通过 24 小时动态双探头 pH 监测诊断为咽喉反流的 106 例患者和我院健康促进中心就诊的 119 例健康对照者。

主要观察指标

采用症状清单-90 修订版问卷评估咽喉反流患者的心理特征,并与健康对照组进行比较。还评估了反流症状指数、反流发现评分、pH 监测参数与症状清单-90 修订版特征之间的相关性。

结果

在症状清单-90 修订版问卷上,咽喉反流患者的九个症状维度和三个总体指标的总均值 T 评分均低于 50。所有患者的总体心理困扰的全球严重程度指数均正常。与对照组相比,除了咽喉反流患者的躯体化量表评分明显较高外,心理特征没有明显差异。反流症状指数与反流次数、总体位下 pH 下降至 4 以下的时间百分比以及上探头的 DeMeester 评分呈显著正相关。症状清单-90 修订版问卷的九个症状维度和三个总体指标与反流症状指数、反流发现评分和 24 小时动态双探头 pH 监测参数均无相关性。

结论

咽喉反流患者没有表现出明显的心理困扰水平,其症状严重程度与反流严重程度呈显著正相关。

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