Kang Jeong Wook, Lee Min Kyeong, Lee Young Chan, Ko Seong-Gyu, Eun Young-Gyu
Department of Biomedical Science and Technology, Graduate School Kyung Hee University Seoul Republic of Korea.
Department of Otolaryngology-Head and Neck Surgery Kyung Hee University School of Medicine, Kyung Hee University Medical Center Seoul Republic of Korea.
Laryngoscope Investig Otolaryngol. 2023 Aug 16;8(5):1288-1293. doi: 10.1002/lio2.1138. eCollection 2023 Oct.
This study aimed to evaluate the relationship between laryngopharyngeal reflux (LPR) and anxiety in patients with LPR.
Prospective, case-control study.
This study was conducted at a tertiary care center.
Sixty-four patients with LPR and 60 healthy controls.
Patients with LPR and healthy individuals ( = 64 and = 60) were enrolled in this study. The Beck Anxiety Inventory (BAI) and reflux symptom index (RSI) were used to evaluate anxiety and reflux-related symptoms, respectively. The BAI can be classified into somatic and subjective symptom scales. The prevalence of anxiety was compared between patients with LPR and healthy individuals. This study evaluated the relationship between BAI and RSI scores.
No statistical difference was found in the prevalence of anxiety between patients with LPR and healthy individuals (42.2% vs. 33.3%). However, the somatic anxiety symptom score was statistically higher in patients with LPR than in healthy individuals ( = .047). We observed a correlation between RSI and somatic anxiety scores of BAI in patients with LPR (rho = 0.286, = .021).
Patients with LPR had more severe somatic anxiety symptoms, and somatic anxiety was associated with their LPR-related symptoms.
本研究旨在评估喉咽反流（LPR）患者中LPR与焦虑之间的关系。
前瞻性病例对照研究。
本研究在一家三级医疗中心进行。
64例LPR患者和60名健康对照者。
本研究纳入了LPR患者和健康个体（分别为64例和60名）。分别使用贝克焦虑量表（BAI）和反流症状指数（RSI）评估焦虑和反流相关症状。BAI可分为躯体症状量表和主观症状量表。比较了LPR患者和健康个体中焦虑的患病率。本研究评估了BAI与RSI评分之间的关系。
LPR患者和健康个体在焦虑患病率方面未发现统计学差异（42.2%对33.3%）。然而，LPR患者的躯体焦虑症状评分在统计学上高于健康个体（P = 0.047）。我们观察到LPR患者中RSI与BAI的躯体焦虑评分之间存在相关性（rho = 0.286，P = 0.021）。
LPR患者有更严重的躯体焦虑症状，且躯体焦虑与他们的LPR相关症状有关。
