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宫内超声暴露:神经迁移研究的流行病学和相关性。

Exposure to ultrasound in utero: epidemiology and relevance of neuronal migration studies.

机构信息

Department of Obstetrics and Gynecology, Lund University, Lund, Sweden.

出版信息

Ultrasound Med Biol. 2010 Aug;36(8):1221-3. doi: 10.1016/j.ultrasmedbio.2010.03.009. Epub 2010 May 5.

Abstract

Despite that epidemiological studies did not indicate negative effects on neurological development of offspring when exposed to diagnostic ultrasound, possible association with nonright-handedness in males could not be excluded. In addition, an experimental study on fetal mice suggested that prolonged ultrasound exposure may cause mild disturbance in neuronal migration. No doubt, further studies are warranted. The present knowledge of the potential bioeffects of ultrasound suggests that, when using ultrasound for examinations in pregnancy, fetal scanning without medical indication should be avoided and that adherence to ALARA principle (use of energy "as low as reasonably achievable") is compulsory.

摘要

尽管流行病学研究并未表明接触诊断性超声会对后代的神经发育产生负面影响,但不能排除其与男性非右利手之间的可能关联。此外,一项针对胎鼠的实验研究表明,长时间的超声暴露可能导致神经元迁移的轻度紊乱。毫无疑问,还需要进一步的研究。目前关于超声潜在生物效应的知识表明,在怀孕期间使用超声进行检查时,应避免无医学指征的胎儿扫描,并强制遵守“合理可达最低辐射”(ALARA)原则(使用尽可能低的能量)。

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