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经导管引流治疗 PD 相关性腹膜炎(PD-related peritonitis)后,持续性症状性腹腔内积液。

Persistent symptomatic intra-abdominal collection after catheter removal for PD-related peritonitis.

机构信息

Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.

出版信息

Perit Dial Int. 2011 Jan-Feb;31(1):34-8. doi: 10.3747/pdi.2009.00185. Epub 2010 May 6.

Abstract

BACKGROUND

Peritoneal dialysis (PD) patients with severe peritonitis require catheter removal. It is often assumed that this approach, together with antibiotics, would eradicate the infection; however, some patients continue to have problems despite catheter removal.

METHOD

We reviewed 30 consecutive PD patients in our center from 1997 to 2008 with recurrent loculated peritoneal collection after catheter removal for severe peritonitis.

RESULTS

Of the 1928 episodes of peritonitis that occurred in 702 patients during the study period, 11.1% required catheter removal and 1.6% developed recurrent peritoneal collection that required percutaneous drainage. Median time to diagnosis of intra-abdominal collection was 12 days after catheter removal (interquartile range 7 - 61 days). In 25 patients (83.3%), aspirate of the abdominal collection was culture negative. In 17 patients (56.7%), the abdominal collection was recurrent and required repeated percutaneous aspiration. Only 3 patients had successful reinsertion of the peritoneal catheter but all had reduced small solute clearance after returning to PD.

CONCLUSION

A small but not negligible proportion of patients with PD-related peritonitis develop recurrent intra-abdominal collection that requires percutaneous drainage after catheter removal. The chance of a successful return to PD is very low in this group of patients. Direct conversion to long-term hemodialysis may avoid unnecessary attempts at peritoneal catheter reinsertion.

摘要

背景

患有严重腹膜炎的腹膜透析(PD)患者需要移除导管。通常认为,这种方法结合抗生素可以消除感染;然而,一些患者尽管移除了导管,仍存在问题。

方法

我们回顾了 1997 年至 2008 年期间在我们中心的 30 名连续 PD 患者,这些患者因严重腹膜炎而移除导管后出现复发性局限性腹膜积脓。

结果

在研究期间,702 名患者发生了 1928 次腹膜炎发作,其中 11.1%需要移除导管,1.6%发生需要经皮引流的复发性腹膜积脓。导管移除后诊断为腹腔积脓的中位时间为 12 天(四分位距 7-61 天)。在 25 名患者(83.3%)中,腹腔积脓的抽吸物培养阴性。在 17 名患者(56.7%)中,腹腔积脓复发,需要反复经皮抽吸。只有 3 名患者成功重新插入腹膜导管,但所有患者在返回 PD 后小溶质清除率均降低。

结论

一小部分但并非可以忽略不计的 PD 相关腹膜炎患者在导管移除后会发展为复发性腹腔内积脓,需要经皮引流。在这群患者中,成功恢复 PD 的机会非常低。直接转为长期血液透析可能避免不必要的腹膜导管再插入尝试。

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