Adams O Peter, Carter Anne O
Faculty of Medical Sciences, The University of the West Indies, Queen Elizabeth Hospital, Bridgetown, Barbados, West Indies.
Open AIDS J. 2010 Mar 12;4:84-7. doi: 10.2174/1874613601004010084.
To predict response rate and validity of a population-based HIV prevalence survey in Barbados using oral fluid, and the method of sample identification preferred by participants.
Persons age 18 to 35 randomly selected from the voters' register to participate in a study of the prevalence of chlamydia and gonorrhoea (STI) were invited to answer a questionnaire.
Of 496 persons selected for the STI study, 88 did not participate, and a further 10 did not answer the questionnaire, leaving 398 respondents. 329 persons or 66% (60% men, 73% women, p = 0.003) of the original 496 persons said that they would be willing to take part in an HIV survey using oral fluid. People indicating willingness to take part in an HIV survey did not differ significantly from non-respondents and those indicating unwillingness to participate by a number of demographic and STI risk factors including age, education level, partnership status, number of partners, condom use, drug use, and STI infection status. For persons willing to participate in a HIV survey, confidential linked sample identification was acceptable to 99.0% (95% CI +/- 1.0), and unlinked identification to 1.6% (95% CI +/- 1.3).
The HIV prevalence estimated by a linked survey would have a reasonable response rate and be valid, as likelihood of participation is not related to infection risk.
运用口腔液预测巴巴多斯一项基于人群的艾滋病毒流行率调查的应答率和有效性，以及参与者偏好的样本识别方法。
从选民登记册中随机选取18至35岁的人员参与一项衣原体和淋病（性传播感染）流行率研究，并邀请他们回答一份问卷。
在入选性传播感染研究的496人中，88人未参与，另有10人未回答问卷，剩余398名受访者。329人（占最初496人的66%，其中男性占60%，女性占73%，p = 0.003）表示愿意参加使用口腔液的艾滋病毒调查。表示愿意参加艾滋病毒调查的人与未受访者以及表示不愿意参与的人在一些人口统计学和性传播感染风险因素方面没有显著差异，这些因素包括年龄、教育水平、伴侣关系状况、伴侣数量、避孕套使用情况、吸毒情况和性传播感染状况。对于愿意参加艾滋病毒调查的人，99.0%（95%置信区间±1.0）的人接受保密关联样本识别，1.6%（95%置信区间±1.3）的人接受非关联识别。
通过关联调查估计的艾滋病毒流行率将有合理的应答率且有效，因为参与可能性与感染风险无关。
