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微波辅助美拉德反应制备糖基化终产物(AGEs)。

Microwave-assisted Maillard reactions for the preparation of advanced glycation end products (AGEs).

机构信息

Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, via P. Giuria 9, 10125 Torino, Italy.

出版信息

Org Biomol Chem. 2010 May 21;8(10):2473-7. doi: 10.1039/c000789g. Epub 2010 Mar 25.

Abstract

The application of microwaves as an efficient form of volumetric heating to promote organic reactions was recognized in the mid-1980 s. It has a much longer history in the food research and industry where microwave irradiation was studied in depth to optimize food browning and the development of desirable flavours from Maillard reactions. The microwave-promoted Maillard reaction is a challenging synthetic method to generate molecular diversity in a straightforward way. In this paper we present a new rapid and efficient one-pot procedure for the preparation of pentosidine and other AGEs under microwave irradiation.

摘要

微波作为一种有效的体积加热方式来促进有机反应的应用在 20 世纪 80 年代中期得到了认可。它在食品研究和工业中有更长的历史,在那里微波辐射被深入研究以优化食品的褐变和从美拉德反应中产生理想的风味。微波促进的美拉德反应是一种具有挑战性的合成方法,可以以直接的方式产生分子多样性。在本文中,我们提出了一种新的快速高效的一锅法,在微波辐射下制备戊糖和其他 AGEs。

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