Departamento de Q. Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, Granada, 18071, Spain.
Chem Soc Rev. 2009 Dec;38(12):3449-62. doi: 10.1039/b909363j. Epub 2009 Aug 4.
The impact of the copper-mediated alkyne-azide cycloadditions on the covalent click immobilization of carbohydrates onto the surface of silica-based materials for the construction of a variety of sophisticated glyco structures and devices are covered in this critical review. The advanced applications of these new bioconjugated hybrid materials are also described (105 references).
本文综述了铜介导的炔烃-叠氮环加成反应在碳水化合物共价点击固定到基于二氧化硅的材料表面上的影响，用于构建各种复杂的糖基结构和器件。还描述了这些新型生物共轭杂化材料的先进应用（105 篇参考文献）。
