Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, China.
Qual Life Res. 2010 Sep;19(7):931-41. doi: 10.1007/s11136-010-9657-x. Epub 2010 May 7.
The aim of the study was to examine the role of neuroticism and mastery in predicting the quality of life (QOL) among Chinese gynecologic cancer survivors.
A total of 184 women participated in this prospective longitudinal study. Participants were to rate their quality of life at baseline (T1) and one year later (T2). Neuroticism as a predictor of QOL was examined by controlling for baseline QOL, sociodemographic, and disease variables using hierarchical linear regression modeling. Mastery as a mediator between the relationship of neuroticism and QOL was also examined.
Bivariate correlations showed that the cancer site, time since diagnosis, neuroticism, and mastery at T1 were related to various aspects of QOL at T1 and T2. After controlling for cancer site, time since diagnosis, QOL at T1, high levels of neuroticism at T1 predicted poor physical and emotional QOL at T2, but mastery at T1 did not mediate the relationship between neuroticism at T1 and QOL at T2.
Neuroticism is a salient personality variable that predicts poor emotional and physical well-being over time. Gynecologic cancer survivors high on neuroticism should be the target for intervention to reduce negative effects during the course of recovery.
本研究旨在探讨神经质和掌控感在预测中国妇科癌症幸存者生活质量（QOL）方面的作用。
共有 184 名女性参与了这项前瞻性纵向研究。参与者需要在基线（T1）和一年后（T2）评估自己的生活质量。采用分层线性回归模型，通过控制基线 QOL、社会人口学和疾病变量，来检验神经质作为 QOL 预测因子的作用。还检验了掌控感在神经质与 QOL 之间关系中的中介作用。
双变量相关分析表明，癌症部位、诊断后时间、T1 时的神经质和掌控感与 T1 和 T2 时 QOL 的各个方面有关。在控制了癌症部位、诊断后时间、T1 时的 QOL 以及 T1 时的高神经质后，T1 时的高神经质预测 T2 时的身体和情绪 QOL 较差，但 T1 时的掌控感并没有中介 T1 时的神经质与 T2 时的 QOL 之间的关系。
神经质是一个显著的人格变量，它会随着时间的推移预测情绪和身体的不良健康状况。神经质水平较高的妇科癌症幸存者应成为干预的目标，以减轻康复过程中的负面影响。
