Division of Pediatric Allergy and Clinical Immunology, Department of Pediatrics, McGill University Health Center, Montreal, Quebec, Canada.
J Allergy Clin Immunol. 2010 Jun;125(6):1327-35. doi: 10.1016/j.jaci.2010.03.015. Epub 2010 May 7.
Recent studies suggest an increased prevalence of food-induced allergy and an increased incidence of food-related anaphylaxis. However, prevalence estimates of food allergies vary considerably between studies.
To determine the prevalence of peanut, tree nut, fish, shellfish, and sesame allergy in Canada.
Using comparable methodology to Sicherer et al in the United States in 2002, we performed a cross-Canada, random telephone survey. Food allergy was defined as perceived (based on self-report), probable (based on convincing history or self-report of physician diagnosis), or confirmed (based on history and evidence of confirmatory tests).
Of 10,596 households surveyed in 2008 and 2009, 3666 responded (34.6% participation rate), of which 3613 completed the entire interview, representing 9667 individuals. The prevalence of perceived peanut allergy was 1.00% (95% CI, 0.80%-1.20%); tree nut, 1.22% (95% CI, 1.00%-1.44%); fish, 0.51% (95% CI, 0.37%-0.65%); shellfish, 1.60% (95% CI, 1.35%-1.86%); and sesame, 0.10% (95% CI, 0.04%-0.17%). The prevalence of probable allergy was 0.93% (95% CI, 0.74%-1.12%); 1.14% (95% CI, 0.92%-1.35%); 0.48% (95% CI, 0.34%-0.61%); 1.42% (95% CI, 1.18%-1.66%); and 0.09% (95% CI, 0.03%-0.15%), respectively. Because of the infrequency of confirmatory tests and the difficulty in obtaining results if performed, the prevalence of confirmed allergy was much lower.
This is the first nationwide Canadian study to determine the prevalence of severe food allergies. Our results indicate disparities between perceived and confirmed food allergy that might contribute to the wide range of published prevalence estimates.
最近的研究表明，食物诱发过敏和与食物相关的过敏反应的发病率都有所增加。然而，食物过敏的流行率在不同的研究中差异很大。
确定加拿大花生、树坚果、鱼类、贝类和芝麻过敏的流行率。
我们使用与 2002 年美国 Sicherer 等人相似的方法，在加拿大进行了一项跨地区的随机电话调查。食物过敏是根据自我报告（基于感知）、可能（基于有说服力的病史或医生诊断的自我报告）或确认（基于病史和确证性测试的证据）来定义的。
在 2008 年和 2009 年调查的 10596 户家庭中，有 3666 户（参与率为 34.6%）做出了回应，其中 3613 户完成了整个访谈，代表了 9667 个人。感知到的花生过敏的流行率为 1.00%（95%可信区间，0.80%-1.20%）；树坚果，1.22%（95%可信区间，1.00%-1.44%）；鱼，0.51%（95%可信区间，0.37%-0.65%）；贝类，1.60%（95%可信区间，1.35%-1.86%）；芝麻，0.10%（95%可信区间，0.04%-0.17%）。可能的过敏的流行率为 0.93%（95%可信区间，0.74%-1.12%）；1.14%（95%可信区间，0.92%-1.35%）；0.48%（95%可信区间，0.34%-0.61%）；1.42%（95%可信区间，1.18%-1.66%）；和 0.09%（95%可信区间，0.03%-0.15%）。由于确证性测试的频率较低，以及如果进行测试则难以获得结果，因此确证性过敏的流行率要低得多。
这是加拿大首次全国性研究，旨在确定严重食物过敏的流行率。我们的结果表明，感知到的食物过敏和确证性食物过敏之间存在差异，这可能导致已发表的流行率估计值差异很大。
