Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat Autònoma de Barcelona, Barcelona, Spain.
Theriogenology. 2010 Jul 15;74(2):277-81. doi: 10.1016/j.theriogenology.2010.02.011. Epub 2010 May 10.
The aim of this study was to estimate the presence of Torque teno sus virus (TTV) species in pig foetuses in order to assess the possible relationship between swine TTV infection and abortion in swine. A total of 98 abortion cases and foetuses collected from 55 pregnant sows at slaughterhouse were analysed by PCR for the presence of Torque teno sus virus 1 (TTV1) and Torque teno sus virus 2 (TTV2). All foetuses were necropsied and relevant tissues were collected, pooled, and submitted to DNA extraction. The overall prevalence of swine TTV1 and TTV2 in aborted foetuses (n = 98) was 17.0% and 29.6%, respectively. For slaughterhouse collected foetuses (n = 55), 10.9% were TTV1 PCR positive and 40.0% were positive for TTV2. There were no statistically significant differences when comparing prevalence of swine TTVs by type of sample (aborted versus slaughterhouse collected foetuses) or by gestation stage. The present work represents the first description of swine TTV infection in pig foetuses at different stages of gestation. Results obtained confirm that vertical transmission is an important route of TTVs dissemination. In addition, data obtained suggest that swine TTVs should not be considered as infectious agents responsible for abortion occurrence.
本研究旨在评估猪胎儿中是否存在扭转型病毒（TTV），以评估猪 TTV 感染与流产之间的可能关系。通过 PCR 分析了来自屠宰场 55 头怀孕母猪的 98 例流产病例和胎儿中 TTV1 和 TTV2 的存在情况。对所有胎儿进行剖检，收集相关组织，混合后提取 DNA。在 98 例流产胎儿（n=98）中，猪 TTV1 和 TTV2 的总流行率分别为 17.0%和 29.6%。对于屠宰场采集的胎儿（n=55），10.9%的 TTV1 PCR 阳性，40.0%的 TTV2 阳性。按样本类型（流产胎儿与屠宰场采集胎儿）或胎龄阶段比较 TTV 的流行率，无统计学差异。本研究首次描述了不同胎龄猪胎儿中的猪 TTV 感染。结果证实，垂直传播是 TTV 传播的重要途径。此外，数据表明，猪 TTV 不应被视为导致流产发生的传染性病原体。
