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[妊娠期糖尿病视网膜病变的进展]

[Progression of diabetic retinopathy during pregnancy].

作者信息

Gaucher D, Saleh M, Sauer A, Averous L, Bourcier T, Speeg-Schatz C

机构信息

Service d'ophtalmologie des hôpitaux universitaires de Strasbourg, nouvel hôpital civil, université Louis-Pasteur, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France.

出版信息

J Fr Ophtalmol. 2010 May;33(5):355-61. doi: 10.1016/j.jfo.2010.03.003. Epub 2010 May 7.

Abstract

Diabetic retinopathy should be carefully monitored during certain risk situations. Indeed, diabetic retinopathy in pregnant type 1 diabetic patients can rapidly progress and threaten vision, as in other situations such as puberty, glycemic equilibration, or ocular surgery. During pregnancy, five major risk factors for progression have been identified: pregnancy itself, diabetic retinopathy grade at baseline, duration of diabetes, important glycated hemoglobin reduction, and high blood pressure. These factors must be taken into account when planning pregnancy in diabetic patients and during the follow-up of their diabetic retinopathy. Diabetic women should be counseled about the risks of progression of their disease before planning pregnancy. Careful eye examination before and during the first trimester should be done in these patients, in order to detect severe non-proliferative diabetic retinopathy and/or high-risk diabetic retinopathy and perform rapid laser treatment if needed. Follow-up visit frequency should be adapted to the severity of the diabetic retinopathy. Very few authors have studied diabetic macular edema during pregnancy. This complication can spontaneously regress postpartum and should not be treated too rapidly.

摘要

在某些风险情况下,应仔细监测糖尿病视网膜病变。事实上,1型糖尿病孕妇的糖尿病视网膜病变可能会迅速进展并威胁视力,在青春期、血糖平衡或眼科手术等其他情况下也是如此。在孕期,已确定了进展的五个主要风险因素:妊娠本身、基线时糖尿病视网膜病变分级、糖尿病病程、糖化血红蛋白显著降低以及高血压。在糖尿病患者计划妊娠时及其糖尿病视网膜病变随访期间,必须考虑这些因素。糖尿病女性在计划妊娠前应被告知其疾病进展的风险。这些患者在孕早期前后应进行仔细的眼部检查,以便检测严重的非增殖性糖尿病视网膜病变和/或高危糖尿病视网膜病变,并在需要时进行快速激光治疗。随访就诊频率应根据糖尿病视网膜病变的严重程度进行调整。很少有作者研究孕期糖尿病黄斑水肿。这种并发症产后可自发消退,不应过早治疗。

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