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食蟹猴雌性腹部脂肪沉积的评估

Assessment of abdominal fat deposition in female cynomolgus monkeys.

作者信息

Laber-Laird K, Shively C A, Karstaedt N, Bullock B C

机构信息

Department of Comparative Medicine, Bowman School of Medicine, Wake Forest University.

出版信息

Int J Obes. 1991 Mar;15(3):213-20.

PMID:2045214
Abstract

Computed tomography (CT) was used to assess abdominal fat distribution in adult, female cynomolgus macaques (Macaca fascicularis). The technique used was similar to that applied in human beings and allowed intra-abdominal, subcutaneous and total abdominal fat to be quantitated in 1 cm thick sections. Correlations between single scans and the average of scans at several levels ranged from r = 0.96 to r = 1.00, indicating that a single scan is representative of abdominal fat distribution. Significant positive correlations were found between body mass index (BMI) and intra-abdominal fat (r = 0.89), subcutaneous fat (r = 0.91) and total abdominal fat (r = 0.90). As BMI increased, fat was preferentially deposited subcutaneously versus intra-abdominally. A unique fat depot, not previously described, was identified dorso-laterally between the internal abdominal oblique and the transversalis muscle. This fat depot was also positively correlated with BMI (r = 0.79). These results indicate that CT can be used in cynomolgus monkeys to quantitate regional fat deposits and that these monkeys resemble human beings in their abdominal fat patterning.

摘要

计算机断层扫描(CT)用于评估成年雌性食蟹猕猴(猕猴属)的腹部脂肪分布。所使用的技术与应用于人类的技术相似,能够在1厘米厚的切片中对腹腔内、皮下和腹部总脂肪进行定量。单次扫描与多个层面扫描平均值之间的相关性范围为r = 0.96至r = 1.00,表明单次扫描可代表腹部脂肪分布。体重指数(BMI)与腹腔内脂肪(r = 0.89)、皮下脂肪(r = 0.91)和腹部总脂肪(r = 0.90)之间存在显著正相关。随着BMI的增加,脂肪优先沉积于皮下而非腹腔内。在腹内斜肌和腹横肌之间的背外侧发现了一个以前未描述过的独特脂肪库。这个脂肪库也与BMI呈正相关(r = 0.79)。这些结果表明,CT可用于食蟹猕猴定量区域脂肪沉积,并且这些猴子在腹部脂肪分布模式上与人类相似。

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