de Gea-García J H, Villegas-Martínez I, Fernández-Vivas M, Sanmartín-Monzó J L, Jara-Rubio R, Martínez-Fresneda M
Unidad de Cuidados Intensivos, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, España.
Med Intensiva. 2010 May;34(4):282-5. doi: 10.1016/j.medin.2009.06.003. Epub 2009 Sep 25.
Cerebral lesions after a stroke present different clinical features depending on the neurological structures affected. Complications after an injury in the respiratory center may lead to prolonged mechanical ventilation. Among these possible complications there is a rare neurological condition called "Ondine's curse" that is caused by spontaneous breathing failure. Patients who suffer this syndrome cannot breathe automatically and need to control their respiration consciously and voluntarily. We report the case of a woman who developed a syndrome of central alveolar hypoventilation secondary to an injury in respiratory center after a hemorrhagic stroke. We have reviewed the etiology, physiopathology, diagnosis and treatment of patients with Ondine's curse.
中风后的脑损伤根据受影响的神经结构呈现出不同的临床特征。呼吸中枢损伤后的并发症可能导致机械通气时间延长。在这些可能的并发症中，有一种罕见的神经系统疾病称为“翁丁氏诅咒”，它是由自主呼吸衰竭引起的。患有这种综合征的患者不能自动呼吸，需要有意识地和自主地控制呼吸。我们报告了一例女性患者，她在出血性中风后因呼吸中枢损伤而出现了中枢性肺泡低通气综合征。我们回顾了翁丁氏诅咒患者的病因、病理生理学、诊断和治疗。
