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本文引用的文献

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Rare and curable renin-mediated hypertension: a series of six cases and a literature review.罕见且可治愈的肾素介导性高血压:6例病例系列及文献综述
J Pediatr Endocrinol Metab. 2016 Feb;29(2):209-16. doi: 10.1515/jpem-2015-0025.
2
Juxtaglomerular cell tumor: a morphological, immunohistochemical and genetic study of six cases.肾小球旁细胞瘤:六例形态学、免疫组织化学和遗传学研究。
Hum Pathol. 2013 Jan;44(1):47-54. doi: 10.1016/j.humpath.2012.04.006. Epub 2012 Aug 29.
3
A kidney tumor in an adolescent with severe hypertension and hypokalemia: an uncommon case--case report and review of the literature on reninoma.一名患有严重高血压和低钾血症的青少年肾肿瘤:罕见病例——病例报告及肾素瘤文献综述
Urol Int. 2010;85(1):121-4. doi: 10.1159/000314339. Epub 2010 May 5.
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Reninoma: case report and literature review.肾素瘤:病例报告及文献综述
J Hypertens. 2008 Feb;26(2):368-73. doi: 10.1097/HJH.0b013e3282f283f3.
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An unusual cause of pediatric hypertension.小儿高血压的一种罕见病因。
J Pediatr. 2007 Aug;151(2):206-12. doi: 10.1016/j.jpeds.2007.04.015.
6
Juxtaglomerular cell tumor of kidney with CD34 and CD117 immunoreactivity: report of 5 cases.具有CD34和CD117免疫反应性的肾球旁细胞瘤:5例报告
Arch Pathol Lab Med. 2006 May;130(5):707-11. doi: 10.5858/2006-130-707-JCTOKW.
7
Metastatic juxtaglomerular cell tumor in a 52-year-old man.一名52岁男性的转移性近球旁细胞瘤。
Am J Surg Pathol. 2004 Aug;28(8):1098-102. doi: 10.1097/01.pas.0000126722.29212.a7.
8
Renin-secreting tumors.肾素分泌瘤
Endocrinol Metab Clin North Am. 1994 Jun;23(2):255-70.
9
Diagnosis and treatment of renin-secreting tumors. Report of three cases.肾素分泌瘤的诊断与治疗。三例报告。
Hypertension. 1984 Sep-Oct;6(5):760-6. doi: 10.1161/01.hyp.6.5.760.
10
The immunocytochemical demonstration of renin in a juxtaglomerular cell tumour by light and electron microscopy.通过光学显微镜和电子显微镜对肾小球旁细胞瘤中肾素进行免疫细胞化学鉴定。
Histopathology. 1983 May;7(3):421-31. doi: 10.1111/j.1365-2559.1983.tb02255.x.

青少年继发性高血压的球旁细胞病因

JUXTAGLOMERULAR CELL CAUSE OF SECONDARY HYPERTENSION IN AN ADOLESCENT.

作者信息

Mezoued M, Habouchi M A, Azzoug S, Mokkedem K, Meskine D

机构信息

University of Algiers, Faculty of Medical Sciences - Department of Endocrinology and Metabolism, Alger, Algeria.

University of Algiers, Faculty of Medical Sciences - Department of Radiology, Alger, Algeria.

出版信息

Acta Endocrinol (Buchar). 2020 Jul-Sep;16(3):359-361. doi: 10.4183/aeb.2020.359.

DOI:10.4183/aeb.2020.359
PMID:33363660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7748224/
Abstract

Reninoma (juxtaglomerular cell tumor) is a rare cause of renin-mediated hypertension. We reported a 18 year old woman with history of hypertension for 3 years. Laboratory findings showed severe hypokalemia and markedly increased levels of renin and aldosterone. Kidney ultrasonography, abdominal computed tomography and magnetic resonance imaging revealed a small mass in the middle region of the right kidney. The patient underwent nephron-sparing surgery; immunohistochemical results demonstrated typical features of reninoma. Postoperatively, blood pressure and potassium levels were normal at 1 month follow-up.

摘要

肾素瘤(球旁细胞瘤)是肾素介导的高血压的罕见病因。我们报告了一名18岁女性,有3年高血压病史。实验室检查结果显示严重低钾血症以及肾素和醛固酮水平显著升高。肾脏超声、腹部计算机断层扫描和磁共振成像显示右肾中部有一个小肿块。患者接受了保留肾单位手术;免疫组化结果显示为肾素瘤的典型特征。术后1个月随访时血压和血钾水平正常。