Zarzaur Ben L, Croce Martin A, Magnotti Louis J, Fabian Timothy C
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
J Trauma. 2010 May;68(5):1134-8. doi: 10.1097/TA.0b013e3181d87488.
Reliance on traditional vital signs (TVS), particularly in older patients, to identify life-threatening shock after injury may be unreliable. Shock index (SI), defined as heart rate divided by systolic blood pressure (SBP), may be a better indicator of early shock after injury than TVS. Multiplying age by SI (age x SI) may be better in older injured patients. We hypothesized that age x SI would be a better predictor of 48-hour mortality in old patients (age, >55 years) compared with TVS, whereas for young patients (age, <or=55 years), SI would be a better predictor than TVS.
Version 8.1 of the National Trauma Data Bank was queried for incidents of blunt, non-neurologic injury occurring during 2007, to patients aged 18 to 81 years. Areas under the receiver operating characteristic curves (AUC) were compared for TVS, SI, and age x SI in young and old patients for predicting 48-hour mortality.
A total of 189,574 incidents were identified. Overall 48-hour mortality was 1.18%. For young patients, there was no difference between SBP (AUC, 0.654) and SI (AUC, 0.655) for predicting 48-hour mortality. For old patients, age x SI (AUC, 0.693) was a better predictor of 48-hour mortality compared with heart rate (AUC, 0.626; p < 0.0001), SBP (AUC, 0.657; p < 0.0002), or SI (AUC, 0.684; p < 0.008).
TVS are inadequate predictors of shock after non-neurologic blunt injury. Using SI in the young and age x SI in old to identify patients at risk for early mortality after blunt injury could result in earlier definitive treatment.
依靠传统生命体征(TVS),尤其是在老年患者中,来识别受伤后危及生命的休克可能并不可靠。休克指数(SI)定义为心率除以收缩压(SBP),与TVS相比,可能是受伤后早期休克的更好指标。将年龄乘以SI(年龄×SI)在老年受伤患者中可能更适用。我们假设,与TVS相比,年龄×SI对老年患者(年龄>55岁)48小时死亡率的预测效果更好,而对于年轻患者(年龄≤55岁),SI比TVS是更好的预测指标。
查询2007年期间国家创伤数据库8.1版本中18至81岁患者发生钝性非神经损伤的事件。比较年轻和老年患者中TVS、SI和年龄×SI预测48小时死亡率的受试者工作特征曲线下面积(AUC)。
共识别出189,574起事件。总体48小时死亡率为1.18%。对于年轻患者,预测48小时死亡率时收缩压(AUC为0.654)和SI(AUC为0.655)之间无差异。对于老年患者,与心率(AUC为0.626;p<0.0001)、收缩压(AUC为0.657;p<0.0002)或SI(AUC为0.684;p<0.008)相比,年龄×SI(AUC为0.693)是48小时死亡率的更好预测指标。
TVS不足以预测非神经钝性损伤后的休克。在年轻患者中使用SI,在老年患者中使用年龄×SI来识别钝性损伤后有早期死亡风险的患者,可能会使确定性治疗更早进行。