一种功能化金纳米粒子辅助的通用反义 DNA 载体。

A functionalized gold nanoparticles-assisted universal carrier for antisense DNA.

机构信息

Graduate School of Life Science and Biotechnology, CHA University, Seongnam 463-836, Republic of Korea.

出版信息

Chem Commun (Camb). 2010 Jun 21;46(23):4151-3. doi: 10.1039/c0cc00103a. Epub 2010 May 10.

PMID:20454745

Abstract

In this study, single-stranded DNA functionalized gold nanoparticles (AuNP GDS) were proved to be efficient gene delivery systems for oligo antisense DNAs specific to any gene of interest without affecting normal cell physiology.

摘要

在这项研究中，证实单链 DNA 功能化金纳米粒子（AuNP GDS）是针对任何感兴趣基因的寡反义 DNA 的有效基因传递系统，而不会影响正常细胞生理。

相似文献

A functionalized gold nanoparticles-assisted universal carrier for antisense DNA.

Chem Commun (Camb). 2010 Jun 21;46(23):4151-3. doi: 10.1039/c0cc00103a. Epub 2010 May 10.

Delivery of shRNA using gold nanoparticle-DNA oligonucleotide conjugates as a universal carrier.

Biochem Biophys Res Commun. 2010 Jul 30;398(3):542-6. doi: 10.1016/j.bbrc.2010.06.115. Epub 2010 Jul 1.

In vitro transcription and translation inhibition via DNA functionalized gold nanoparticles.

Nanotechnology. 2010 Dec 17;21(50):505101. doi: 10.1088/0957-4484/21/50/505101. Epub 2010 Nov 22.

Cell culture and xenograft-bearing animal studies of radiolabeled antisense DNA carrier nanoparticles with streptavidin as a linker.

J Nucl Med. 2007 Nov;48(11):1845-52. doi: 10.2967/jnumed.106.039339.

Nuclear penetration of surface functionalized gold nanoparticles.

Toxicol Appl Pharmacol. 2009 Jun 1;237(2):196-204. doi: 10.1016/j.taap.2009.03.009. Epub 2009 Mar 27.

Association temperature governs structure and apparent thermodynamics of DNA-gold nanoparticles.

Biophys Chem. 2007 Mar;126(1-3):124-31. doi: 10.1016/j.bpc.2006.05.020. Epub 2006 Jun 6.

Modulation of biological processes in the nucleus by delivery of DNA oligonucleotides conjugated with gold nanoparticles.

Biomaterials. 2011 Apr;32(10):2593-604. doi: 10.1016/j.biomaterials.2010.11.074. Epub 2011 Jan 19.

Enzymatic disassembly of DNA-gold nanostructures.

Small. 2007 Apr;3(4):590-4. doi: 10.1002/smll.200600494.

Periodic assembly of nanospecies on repetitive DNA sequences generated on gold nanoparticles by rolling circle amplification.

Methods Mol Biol. 2008;474:79-90. doi: 10.1007/978-1-59745-480-3_6.

Contribution of nanoscale curvature to number density of immobilized DNA on gold nanoparticles.

Langmuir. 2009 Feb 3;25(3):1285-8. doi: 10.1021/la803385x.

引用本文的文献

Silencing of heat shock protein 90 (hsp90): Effect on development and infectivity of Ichthyophthirius multifiliis.

BMC Vet Res. 2023 Mar 18;19(1):62. doi: 10.1186/s12917-023-03613-4.

PEGylated Gold Nanoparticles Grafted with N-Acetyl-L-Cysteine for Polymer Modification.

Nanomaterials (Basel). 2021 May 28;11(6):1434. doi: 10.3390/nano11061434.

A Comparison Between Recombinant GAPDH Proteins and GAPDH Encoding mRNA Conjugated to Lipids as Cross-Reactive Vaccines for , and .

Front Immunol. 2021 Apr 19;12:632304. doi: 10.3389/fimmu.2021.632304. eCollection 2021.

A Review on the Synthesis and Functionalization of Gold Nanoparticles as a Drug Delivery Vehicle.

Int J Nanomedicine. 2020 Dec 7;15:9823-9857. doi: 10.2147/IJN.S279094. eCollection 2020.

MXD3 antisense oligonucleotide with superparamagnetic iron oxide nanoparticles: A new targeted approach for neuroblastoma.

Nanomedicine. 2020 Feb;24:102127. doi: 10.1016/j.nano.2019.102127. Epub 2019 Nov 26.

Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates.

Genes (Basel). 2018 Feb 6;9(2):74. doi: 10.3390/genes9020074.

LRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycle.

Oncogenesis. 2018 Jan 23;7(1):3. doi: 10.1038/s41389-017-0019-1.

Functionalized Gold Nanoparticles and Their Biomedical Applications.

Nanomaterials (Basel). 2011 Jun 14;1(1):31-63. doi: 10.3390/nano1010031.

Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems.

Gene Ther. 2017 Mar;24(3):133-143. doi: 10.1038/gt.2017.5. Epub 2017 Jan 17.

Off to the organelles - killing cancer cells with targeted gold nanoparticles.

Theranostics. 2015 Jan 21;5(4):357-70. doi: 10.7150/thno.10657. eCollection 2015.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

一种功能化金纳米粒子辅助的通用反义 DNA 载体。

A functionalized gold nanoparticles-assisted universal carrier for antisense DNA.

机构信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

一种功能化金纳米粒子辅助的通用反义 DNA 载体。

A functionalized gold nanoparticles-assisted universal carrier for antisense DNA.

机构信息

出版信息

相似文献

引用本文的文献