一种功能化金纳米粒子辅助的通用反义 DNA 载体。
A functionalized gold nanoparticles-assisted universal carrier for antisense DNA.
机构信息
Graduate School of Life Science and Biotechnology, CHA University, Seongnam 463-836, Republic of Korea.
出版信息
Chem Commun (Camb). 2010 Jun 21;46(23):4151-3. doi: 10.1039/c0cc00103a. Epub 2010 May 10.
PMID:20454745
Abstract
In this study, single-stranded DNA functionalized gold nanoparticles (AuNP GDS) were proved to be efficient gene delivery systems for oligo antisense DNAs specific to any gene of interest without affecting normal cell physiology.
摘要
在这项研究中，证实单链 DNA 功能化金纳米粒子（AuNP GDS）是针对任何感兴趣基因的寡反义 DNA 的有效基因传递系统，而不会影响正常细胞生理。
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