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室内环境香烟烟雾暴露与成年人的呼吸道症状和肺功能下降有关,但与其他吸入性颗粒物无关。

Indoor exposure to environmental cigarette smoke, but not other inhaled particulates associates with respiratory symptoms and diminished lung function in adults.

机构信息

Research Centre for Prevention and Health, Glostrup, Denmark.

出版信息

Respirology. 2010 Aug;15(6):993-1000. doi: 10.1111/j.1440-1843.2010.01758.x. Epub 2010 Apr 23.

DOI:10.1111/j.1440-1843.2010.01758.x
PMID:20456673
Abstract

BACKGROUND AND OBJECTIVE

Exposure to particulate matter (PM) can induce airway inflammation and exacerbation of asthma. However, there is limited knowledge about the effects of exposure to indoor sources of PM. We investigated the associations between self-reported exposure to indoor sources of PM and lower airway symptoms and lung function.

METHODS

A population-based cross-sectional study of 3471 persons aged 18-69 years was conducted. Information about exposure to indoor sources of PM and airway symptoms was obtained from a self-administered questionnaire.

RESULTS

Exposure to wood stoves, candles and gas cookers was not significantly associated with an increased prevalence of lower respiratory symptoms or decreased lung function. In contrast, persons exposed to environmental tobacco smoke for >5 h/day had a significantly increased risk of 'wheeze' (OR 1.69, 95% CI: 1.24-2.30) and 'chronic cough' (OR 1.57, 95% CI: 1.12-2.20), as well as decreased lung function (FEV(1)% predicted), compared with those who were not exposed. Similar trends were observed in never smokers.

CONCLUSIONS

In this cross-sectional study of an adult general population, self-reported exposure to environmental tobacco smoke, but not self-reported exposure to wood stoves, candles or gas cookers, appeared to be associated with an increased prevalence of lower airway symptoms and decreased lung function.

摘要

背景与目的

颗粒物(PM)暴露可诱发气道炎症和哮喘恶化。然而,我们对于室内 PM 来源的暴露所产生的影响知之甚少。我们研究了自我报告的室内 PM 来源暴露与下呼吸道症状和肺功能之间的关联。

方法

我们进行了一项基于人群的横断面研究,共纳入了 3471 名 18-69 岁的人群。通过自我管理问卷获取了关于室内 PM 来源暴露和气道症状的信息。

结果

暴露于柴火炉、蜡烛和煤气炉与下呼吸道症状的患病率增加或肺功能下降无关。相比之下,每日暴露于环境烟草烟雾>5 小时的人群,“喘息”(OR 1.69,95%CI:1.24-2.30)和“慢性咳嗽”(OR 1.57,95%CI:1.12-2.20)的患病风险显著增加,并且肺功能(FEV1%pred)也下降,与未暴露的人群相比。在从不吸烟者中也观察到了类似的趋势。

结论

在这项成人一般人群的横断面研究中,自我报告的环境烟草烟雾暴露,而不是自我报告的柴火炉、蜡烛或煤气炉暴露,似乎与下呼吸道症状的患病率增加和肺功能下降有关。

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