Department of Practice and Policy, School of Pharmacy, University of London, UK.
J Clin Pharm Ther. 2010 Apr;35(2):127-38. doi: 10.1111/j.1365-2710.2009.01048.x.
As an alternative to the usual insulin injections, insulin pumps have been introduced as an advanced method of insulin delivery for managing type 1 diabetes mellitus patients. This review documents the history of insulin pump development and the production of 'smart pumps' that offer patients greater dosing accuracy, flexibility, and ease of use. This has resulted in an increase in the number of insulin pump users around the world. This paper also provides a comprehensive survey of the pumps currently available on the market and their specifications. Unique features of each product and the drawbacks are addressed in the review. The future direction of insulin pump development is targeted toward closing the loop, to allow feedback control between an insulin pump and a glucose sensor, and hence finer adjustment of insulin delivery rates as required.
作为常规胰岛素注射的替代方法，胰岛素输注泵作为一种先进的胰岛素给药方法已被引入，用于管理 1 型糖尿病患者。本综述记录了胰岛素泵发展的历史以及“智能泵”的生产，为患者提供了更高的给药准确性、灵活性和易用性。这导致全球使用胰岛素泵的人数增加。本文还对市场上现有的各种胰岛素泵及其规格进行了全面调查。本文还对每种产品的独特功能和缺点进行了综述。胰岛素泵的未来发展方向是实现闭环控制，允许胰岛素泵和葡萄糖传感器之间进行反馈控制，从而根据需要更精细地调整胰岛素输送率。
