Taylor Peter James, Awenat Yvonne, Gooding Patricia, Johnson Judith, Pratt Daniel, Wood Alex, Tarrier Nicholas
School of Psychological Sciences, University of Manchester, Manchester, United Kingdom.
J Nerv Ment Dis. 2010 May;198(5):343-8. doi: 10.1097/NMD.0b013e3181da8545.
Mental health research may pose a risk to those who participate in it, especially for potentially vulnerable groups such as those diagnosed with schizophrenia. The current study aimed to investigate the subjective experience of research participation in this group. Seventy-nine individuals with diagnoses of schizophrenia spectrum disorders who had taken part in research looking at suicide were asked to provide feedback about their experiences. Responses were analyzed using qualitative and quantitative methods. Results indicate that negative feedback concerning participation was rare, occurring in 2.5% to 15.2% of responses. Positive feedback was more frequent, occurring in 45.6% to 60.8% of responses. Qualitative thematic analysis identified 5 key themes in participants' responses: Altruism, Value of being involved in research, Therapeutic effect, Enjoyable experience and Negative experiences. The results support the view that mental health research in this group can be ethically viable.
心理健康研究可能会对参与研究的人构成风险，尤其是对于那些潜在的弱势群体，比如被诊断患有精神分裂症的人。当前的研究旨在调查这一群体参与研究的主观体验。79名被诊断患有精神分裂症谱系障碍且参与过自杀相关研究的个体被要求提供有关其经历的反馈。采用定性和定量方法对回复进行分析。结果表明，关于参与研究的负面反馈很少见，占回复的2.5%至15.2%。正面反馈更为常见，占回复的45.6%至60.8%。定性主题分析确定了参与者回复中的5个关键主题：利他主义、参与研究的价值、治疗效果、愉快的体验和负面体验。结果支持了这样一种观点，即针对这一群体的心理健康研究在伦理上是可行的。
