Doblin R E, Kleiman M A
Kennedy School of Government, Cambridge, MA 02138.
J Clin Oncol. 1991 Jul;9(7):1314-9. doi: 10.1200/JCO.1991.9.7.1314.
A random-sample, anonymous survey of the members of the American Society of Clinical Oncology (ASCO) was conducted in spring 1990 measuring the attitudes and experiences of American oncologists concerning the antiemetic use of marijuana in cancer chemotherapy patients. The survey was mailed to about one third (N = 2,430) of all United States-based ASCO members and yielded a response rate of 43% (1,035). More than 44% of the respondents report recommending the (illegal) use of marijuana for the control of emesis to at least one cancer chemotherapy patient. Almost one half (48%) would prescribe marijuana to some of their patients if it were legal. As a group, respondents considered smoked marijuana to be somewhat more effective than the legally available oral synthetic dronabinol ([THC] Marinol; Unimed, Somerville, NJ) and roughly as safe. Of the respondents who expressed an opinion, a majority (54%) thought marijuana should be available by prescription. These results bear on the question of whether marijuana has a "currently accepted medical use," at issue in an ongoing administrative and legal dispute concerning whether marijuana in smoked form should be available by prescription along with synthetic THC in oral form. This survey demonstrates that oncologists' experience with the medical use of marijuana is more extensive, and their opinions of it are more favorable, than the regulatory authorities appear to have believed.
1990年春季,针对美国临床肿瘤学会(ASCO)会员开展了一项随机抽样的匿名调查,以了解美国肿瘤学家对癌症化疗患者使用大麻止吐的态度和经验。该调查邮件寄给了约三分之一(N = 2430)总部位于美国的ASCO会员,回复率为43%(1035份)。超过44%的受访者报告称,他们至少向一名癌症化疗患者推荐过(非法)使用大麻来控制呕吐。如果大麻合法,近一半(48%)的受访者会给他们的一些患者开大麻处方。总体而言,受访者认为吸食大麻比合法可得的口服合成屈大麻酚([THC] 美沙酮;Unimed,新泽西州萨默维尔)更有效一些,且安全性大致相当。在表达了意见的受访者中,多数(54%)认为大麻应该凭处方获取。这些结果关系到大麻是否具有“目前被认可的医疗用途”这一问题,这也是当前一场关于吸食形式的大麻是否应与口服形式的合成THC一样凭处方获取的行政和法律争端中的争议点。这项调查表明,肿瘤学家对大麻医疗用途的经验更为广泛,且他们对大麻的看法比监管机构似乎所认为的更为积极。