Division of Neurology, Faculty of Medicine, Thammasat University, Klong Luang, Pathumthani, Thailand.
Angiology. 2010 Nov;61(8):789-92. doi: 10.1177/0003319710369793. Epub 2010 May 12.
We looked for risk factors for significant carotid stenosis (CS) in patients with ischemic stroke. We included all patients treated for an ischemic stroke/transient ischemic attack (TIA) and had a carotid duplex done from August 2006 to November 2008. A total of 458 patients were included. Significant CS of the extracranial internal carotid artery and the common carotid artery were found in 10.9% (50 of 458 patients). Age (≥65 years old) was the independent risk factor for CS (OR 4.0, P < .0001). The patients with a CS had more history of coronary artery disease (12% vs 8%, P = .32), prior ischemic stroke (18% vs 11%, P = .17), atrial fibrillation (10% vs 5%, P = .19), and smoking (28% vs 24%, P = .18) compared with the patients without CS. The evaluation of the carotid arteries should be recommended in patients with ischemic stroke/TIA, especially in the older ones (≥65 years old).
我们研究了缺血性脑卒中患者发生颈动脉狭窄(CS)的危险因素。我们纳入了 2006 年 8 月至 2008 年 11 月间所有因缺血性脑卒中/短暂性脑缺血发作(TIA)而接受治疗并接受颈动脉双功能超声检查的患者。共纳入了 458 例患者。发现颅外颈内动脉和颈总动脉存在明显 CS 的患者占 10.9%(458 例患者中有 50 例)。年龄(≥65 岁)是 CS 的独立危险因素(OR 4.0,P<.0001)。与无 CS 的患者相比,CS 患者具有更多的冠心病病史(12% vs 8%,P=.32)、既往缺血性脑卒中病史(18% vs 11%,P=.17)、心房颤动病史(10% vs 5%,P=.19)和吸烟史(28% vs 24%,P=.18)。对于缺血性脑卒中/TIA 患者,尤其是年龄较大(≥65 岁)的患者,应推荐评估颈动脉。