Department of Epidemiology Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Am J Clin Nutr. 2010 Jul;92(1):203-10. doi: 10.3945/ajcn.2010.29269. Epub 2010 May 12.
There is uncertainty over the nutrition-related benefits to health of consuming organic foods.
We sought to assess the strength of evidence that nutrition-related health benefits could be attributed to the consumption of foods produced under organic farming methods.
We systematically searched PubMed, ISI Web of Science, CAB Abstracts, and Embase between 1 January 1958 and 15 September 2008 (and updated until 10 March 2010); contacted subject experts; and hand-searched bibliographies. We included peer-reviewed articles with English abstracts if they reported a comparison of health outcomes that resulted from consumption of or exposure to organic compared with conventionally produced foodstuffs.
From a total of 98,727 articles, we identified 12 relevant studies. A variety of different study designs were used; there were 8 reports (67%) of human studies, including 6 clinical trials, 1 cohort study, and 1 cross-sectional study, and 4 reports (33%) of studies in animals or human cell lines or serum. The results of the largest study suggested an association of reported consumption of strictly organic dairy products with a reduced risk of eczema in infants, but the majority of the remaining studies showed no evidence of differences in nutrition-related health outcomes that result from exposure to organic or conventionally produced foodstuffs. Given the paucity of available data, the heterogeneity of study designs used, exposures tested, and health outcomes investigated, no quantitative meta-analysis was justified.
From a systematic review of the currently available published literature, evidence is lacking for nutrition-related health effects that result from the consumption of organically produced foodstuffs.
目前对于食用有机食品是否对健康有益还存在不确定性，尤其是在营养方面。
我们试图评估有多少证据表明食用有机农业生产的食品与营养相关的健康益处有关。
我们系统地检索了 1958 年 1 月 1 日至 2008 年 9 月 15 日期间的 PubMed、ISI Web of Science、CAB Abstracts 和 Embase（并更新至 2010 年 3 月 10 日）；联系了相关领域的专家；并查阅了参考文献。如果文章报道了有机食品与传统食品消费或暴露相比对健康结果的影响，并提供了英文摘要，我们将其纳入研究。
在总共 98727 篇文章中，我们确定了 12 项相关研究。研究设计各不相同，其中 8 项是人体研究报告（占 67%），包括 6 项临床试验、1 项队列研究和 1 项横断面研究，4 项是动物或人细胞系或血清研究（占 33%）。最大规模研究的结果表明，严格食用有机奶制品与婴儿湿疹风险降低之间存在关联，但其余大多数研究并未显示出食用有机或传统食品在营养相关健康结果方面存在差异的证据。鉴于现有数据的匮乏、所使用的研究设计、测试的暴露因素和研究的健康结果的异质性，没有进行定量荟萃分析。
从目前已发表文献的系统评价来看，缺乏有机生产食品消费与营养相关健康效应之间的证据。
