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[与甲状腺功能减退相关的丘疹性黏蛋白病]

[Papular mucinosis associated with hypothyroidism].

作者信息

Volpato Morgana Boeno, Jaime Tatiana Jerez, Proença Martha Pisani, Gripp Alexandre Carlos, Alves Maria de Fátima Guimarães Scotelaro

机构信息

Universidade do Estado do Rio de Janeiro, RJ, Brasil.

出版信息

An Bras Dermatol. 2010 Jan-Feb;85(1):89-92. doi: 10.1590/s0365-05962010000100014.

DOI:10.1590/s0365-05962010000100014
PMID:20464094
Abstract

Papular mucinosis or lichen myxedematosus is an idiopathic disorder characterized by papules, nodules or plaques caused by mucin deposition in the dermis, in the absence of thyroid disease. The present report describes an atypical case with exuberant lesions in the form of plaques, associated with subclinical hypothyroidism. In cutaneous mucinosis, there is an abnormal quantity of mucin in the dermis. In traditional classifications of papular mucinosis, an absence of thyroid disease constitutes a diagnostic criterion. A few cases of the disease have been reported in association with hypothyroidism constituting, as in the present case, atypical lichen myxedematosus. It is therefore suggested that the presence of thyroid disease should not be considered an exclusion criterion for the diagnosis of this condition.

摘要

丘疹性黏蛋白沉积症或黏液水肿性苔藓是一种特发性疾病,其特征为真皮内黏蛋白沉积导致的丘疹、结节或斑块,且无甲状腺疾病。本报告描述了一例非典型病例,其表现为斑块形式的大量皮损,并伴有亚临床甲状腺功能减退。在皮肤黏蛋白沉积症中,真皮内存在异常数量的黏蛋白。在丘疹性黏蛋白沉积症的传统分类中,无甲状腺疾病是一项诊断标准。已有少数该疾病病例报告与甲状腺功能减退相关,如本病例,构成非典型黏液水肿性苔藓。因此,有人提出甲状腺疾病的存在不应被视为诊断该病的排除标准。

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[Papular mucinosis associated with hypothyroidism].[与甲状腺功能减退相关的丘疹性黏蛋白病]
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Papular mucinosis, or localized lichen myxedematosis (LM) (discrete papular type).丘疹性黏蛋白沉积症,或局限性黏液性苔藓(LM)(离散丘疹型)。
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Am J Dermatopathol. 2019 Jul;41(7):505-510. doi: 10.1097/DAD.0000000000001335.

引用本文的文献

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Scleromyxoedema and Thyroid Disease: A Case Report.硬化性黏液水肿与甲状腺疾病:一例报告
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Case for diagnosis. Multiple infiltrated plaques in a patient with human immunodeficiency virus and hepatitis C co-infection: lichen myxedematosus.诊断病例。一名同时感染人类免疫缺陷病毒和丙型肝炎的患者出现多处浸润性斑块:黏液水肿性苔藓。
An Bras Dermatol. 2023 May-Jun;98(3):398-400. doi: 10.1016/j.abd.2021.10.017. Epub 2023 Feb 24.
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Discrete Papular Lichen Myxedematosus and Scleromyxedema with Hypothyroidism: A Report of Two Cases.
伴有甲状腺功能减退的离散性丘疹性黏液性苔藓和硬化性黏液水肿:两例报告
Case Rep Dermatol. 2019 Mar 19;11(1):64-70. doi: 10.1159/000498881. eCollection 2019 Jan-Apr.
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A Case of Autoimmune Polyglandular Syndrome .ype 2 Associated with Atypical Form of Scleromyxedema.1例2型自身免疫性多腺体综合征合并非典型硬肿病样黏液水肿
Ethiop J Health Sci. 2016 Sep;26(5):503-507.
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Case for diagnosis. Lichen myxedematosus.诊断病例。黏液性水肿性苔藓。
An Bras Dermatol. 2016 Nov-Dec;91(6):842-843. doi: 10.1590/abd1806-4841.20165725.
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A case of scleromyxoedema with thyroid dysfunction.一例伴有甲状腺功能障碍的硬化性黏液水肿病例。
Indian J Dermatol. 2014 Sep;59(5):524-5. doi: 10.4103/0019-5154.139925.