Volpato Morgana Boeno, Jaime Tatiana Jerez, Proença Martha Pisani, Gripp Alexandre Carlos, Alves Maria de Fátima Guimarães Scotelaro
Universidade do Estado do Rio de Janeiro, RJ, Brasil.
An Bras Dermatol. 2010 Jan-Feb;85(1):89-92. doi: 10.1590/s0365-05962010000100014.
Papular mucinosis or lichen myxedematosus is an idiopathic disorder characterized by papules, nodules or plaques caused by mucin deposition in the dermis, in the absence of thyroid disease. The present report describes an atypical case with exuberant lesions in the form of plaques, associated with subclinical hypothyroidism. In cutaneous mucinosis, there is an abnormal quantity of mucin in the dermis. In traditional classifications of papular mucinosis, an absence of thyroid disease constitutes a diagnostic criterion. A few cases of the disease have been reported in association with hypothyroidism constituting, as in the present case, atypical lichen myxedematosus. It is therefore suggested that the presence of thyroid disease should not be considered an exclusion criterion for the diagnosis of this condition.
丘疹性黏蛋白沉积症或黏液水肿性苔藓是一种特发性疾病,其特征为真皮内黏蛋白沉积导致的丘疹、结节或斑块,且无甲状腺疾病。本报告描述了一例非典型病例,其表现为斑块形式的大量皮损,并伴有亚临床甲状腺功能减退。在皮肤黏蛋白沉积症中,真皮内存在异常数量的黏蛋白。在丘疹性黏蛋白沉积症的传统分类中,无甲状腺疾病是一项诊断标准。已有少数该疾病病例报告与甲状腺功能减退相关,如本病例,构成非典型黏液水肿性苔藓。因此,有人提出甲状腺疾病的存在不应被视为诊断该病的排除标准。