Dermatology, Pediatrics, and Pathology, New Jersey Medical School, Newark, NJ 07103, USA.
Int J Dermatol. 2010 Mar;49(3):257-61. doi: 10.1111/j.1365-4632.2008.03915.x.
Pityriasis lichenoides et varioliformis acuta (PLEVA), or Mucha-Habermann disease (MHD), is a cutaneous disorder evident with crops of erythematous macules and papules, usually on the trunk and flexural areas of the extremities. Its etiology remains unknown. PLEVA is speculated to be an inflammatory reaction triggered by certain infectious agents, an inflammatory response secondary to T-cell dyscrasia, or an immune complex-mediated hypersensitivity. Histologic examination of a skin biopsy specimen is the standard for the identification of PLEVA, but definitive diagnosis may be difficult. Apart from the febrile ulcerative variant, which may be fatal, PLEVA tends to be self-limited in its course. Treatment is targeted mainly at the symptomatic relief of pruritus.
急性痘疮样苔藓样糠疹（PLEVA），又称 Mucha-Habermann 病（MHD），是一种皮肤疾病，其特征为红斑性丘疹和斑丘疹的皮疹分批出现，通常发生于躯干和四肢的屈侧。其病因尚不清楚。PLEVA 被认为是由某些感染因子引发的炎症反应，或是 T 细胞紊乱继发的炎症反应，或是免疫复合物介导的过敏反应。皮肤活组织检查是 PLEVA 的标准诊断方法，但明确诊断可能具有一定难度。除了可能致命的发热性溃疡性变异型外，PLEVA 的病程通常具有自限性。治疗主要针对瘙痒的症状缓解。
