Downstate Medical Center, State University of New York, New York, NY, USA.
G Ital Dermatol Venereol. 2010 Apr;145(2):229-44.
Skin serves as a window to the wellbeing and disease in a person. The recognition of cutaneous markers of endocrine neoplasia can allow for the early diagnosis of tumors, for early treatment and ultimately prevention of morbidity and mortality secondary to malignancy. The following review outlines the various endocrine neoplasias which can present with cutaneous manifestations. The pathogenesis and general manifestations are reviewed as well as the cutaneous manifestations of the endocrine neoplasia. Diagnosis and management are discussed. A summary of the familial endocrine neoplastic syndromes, including the six Multiple Endocrine Neoplasia Syndromes are reviewed. A current understanding of this subject will allow for better diagnosis and recognition of endocrine tumors as they present with skin signs and symptoms.
皮肤是了解一个人整体健康和疾病的窗口。识别皮肤内分泌肿瘤标志物可以实现肿瘤的早期诊断，从而进行早期治疗，最终预防因恶性肿瘤而导致的发病率和死亡率。以下综述概述了可能出现皮肤表现的各种内分泌肿瘤。本文回顾了发病机制和一般表现，以及内分泌肿瘤的皮肤表现。讨论了诊断和治疗。总结了家族性内分泌肿瘤综合征，包括六种多发性内分泌肿瘤综合征。目前对这一主题的认识将有助于更好地诊断和识别内分泌肿瘤，因为它们会出现皮肤体征和症状。
