Co M S, Queen C
Protein Design Labs, Inc., Mountain View, California 94043.
Nature. 1991 Jun 6;351(6326):501-2. doi: 10.1038/351501a0.
Protein engineering has made it possible to combine the binding sites of murine antibodies with human antibody regions. Antibodies constructed in this way have important advantages for therapy.
蛋白质工程使得将鼠源抗体的结合位点与人源抗体区域相结合成为可能。以这种方式构建的抗体在治疗方面具有重要优势。
