Monash Alfred Psychiatry Research Centre, School of Psychology and Psychiatry, Monash University and the Alfred, Australia.
Neuropsychologia. 2010 Jul;48(9):2675-80. doi: 10.1016/j.neuropsychologia.2010.05.014. Epub 2010 May 12.
Putative measures of mirror neuron activity suggest that mirror neurons respond preferentially to biological motion, but it remains unclear whether enhanced cortical activity occurs during the observation of any behaviour, or whether that behaviour needs to be associated with a particular object or goal. Forty-three healthy adults completed a transcranial magnetic stimulation (TMS) experiment that assessed corticospinal excitability while viewing intransitive and transitive hand gestures (compared with the presentation of a static hand). Visual presentations were designed to control for motoric and stimulus properties. A significant increase in corticospinal excitability (putatively reflecting mirror neuron activation) was seen only during the observation of transitive behaviour. These findings are consistent with the notion that human hand-related mirror neurons are sensitive to object- and goal-directed behaviour, rather than biological motion per se.
假设的镜像神经元活动测量表明，镜像神经元优先对生物运动做出反应，但目前尚不清楚在观察任何行为时是否会增强皮质活动，或者该行为是否需要与特定的物体或目标相关联。43 名健康成年人完成了一项经颅磁刺激（TMS）实验，该实验在观察非传递性和传递性手部动作（与静态手部动作相比）时评估了皮质脊髓兴奋性。视觉呈现旨在控制运动和刺激特性。只有在观察到传递性行为时，才会观察到皮质脊髓兴奋性的显著增加（推测反映了镜像神经元的激活）。这些发现与人类手部相关的镜像神经元对手和目标导向的行为敏感，而不是对生物运动本身敏感的观点一致。
