虚拟结肠镜检查与光学结肠镜检查。
Virtual colonoscopy vs optical colonoscopy.
作者信息
Liang Zhengrong, Richards Robert
机构信息
IEEE Fellow, Professor of Radiology, Computer Science and Biomedical Engineering, School of Medicine, L4-120, Health Sciences Center, Stony Brook University, Stony Brook, NY 11794-8460, USA, (Tel): +1 631-444-7837, (Fax): +1 631-444-6450.
出版信息
Expert Opin Med Diagn. 2010 Mar 1;4(2):159-169. doi: 10.1517/17530051003658736.
IMPORTANCE OF THE FIELD
The high prevalence of colon carcinoma combined with the low compliance of currently recommended screening guidelines explains the continued high mortality rate of colon cancer. Utilizing a strategy of virtual colonoscopy (VC) in asymptomatic patients over 50, with optical colonoscopy (OC) follow-up for removal of detected adenomatous polyps may result in lowering the colon cancer death rate. However, the screening potential of VC has not yet been widely recognized. Debates and doubts of its potential benefits have been frequently seen in the literature since VC was first reported in 1994. AREAS COVERED IN THIS REVIEW: This article reviews the currently available screening options and discuss their advantages and drawbacks. TAKE HOME MESSAGE: VC has many advantages over the existing screening options and its several drawbacks can be mitigated so that it would become a valuable screening modality. A strategy that utilizes VC for population-based screening over the age of 50 and OC for screening high-risk individuals and those with positive VC findings would result in a significantly reduced rate of colon cancer deaths.
该领域的重要性
结肠癌的高发病率与当前推荐筛查指南的低依从性导致结肠癌死亡率持续居高不下。对50岁以上无症状患者采用虚拟结肠镜检查（VC）策略，并通过光学结肠镜检查（OC）对检测到的腺瘤性息肉进行后续切除，可能会降低结肠癌死亡率。然而，VC的筛查潜力尚未得到广泛认可。自1994年首次报道VC以来，其潜在益处一直存在争议和质疑。 本综述涵盖的领域：本文回顾了目前可用的筛查方法，并讨论了它们的优缺点。 关键信息：与现有的筛查方法相比，VC有许多优点，其几个缺点也可以得到缓解，从而使其成为一种有价值的筛查方式。采用VC对50岁以上人群进行基于人群的筛查，以及采用OC对高危个体和VC检查结果呈阳性的个体进行筛查的策略，将显著降低结肠癌死亡率。
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