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在捷克共和国进行的首次描述性基于人群的研究中,银屑病关节炎、强直性脊柱炎和反应性关节炎的发病率和患病率。

Incidence and prevalence of psoriatic arthritis, ankylosing spondylitis, and reactive arthritis in the first descriptive population-based study in the Czech Republic.

机构信息

Institute of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Czech Republic.

出版信息

Scand J Rheumatol. 2010 Aug;39(4):310-7. doi: 10.3109/03009740903544212.

Abstract

OBJECTIVE

To estimate the annual incidence and prevalence of psoriatic arthritis (PsA), ankylosing spondylitis (AS), and reactive arthritis (ReA) in a sample of the Czech population.

METHODS

The population-based study was conducted in two regions of the Czech Republic (with a total population of 186000 inhabitants) in 2002-2003. Incident cases were registered on condition of confirming a definite diagnosis according to existing classification criteria during the study period (1 March 2002 to 1 March 2003). Prevalence was studied on the basis of identification of established diagnoses (before 1 March 2002) from registers of living patients of participating rheumatologists and other specialists. The age-standardized estimates of incidence and prevalence were calculated using the European standard population.

RESULTS

The total annual incidence of PsA in adults aged >or= 16 years was 3.6/100000 [95% confidence interval (CI) 1.4-7.6/100000] and the prevalence of PsA was 49.1/100000 (95% CI 39.5-60.4/100000). The annual incidence of AS in adults was 6.4/100000 (95% CI 3.3-11.3/100000) and the prevalence of AS was 94.2/100000 (95% CI 80.8-109.2/100 000). The annual incidence of ReA in adults was 9.3/100000 (95% CI 5.5-14.8/100000) and the prevalence of ReA was 91.3/100000 (95% CI 78.1-106.2/100000).

CONCLUSION

The annual incidence and prevalence rates of PsA, AS, and ReA in the first population-based survey in the Czech Republic compared well with data reported from other countries.

摘要

目的

在捷克人群样本中估算银屑病关节炎(PsA)、强直性脊柱炎(AS)和反应性关节炎(ReA)的年发病率和患病率。

方法

该基于人群的研究于 2002-2003 年在捷克共和国的两个地区(总人口为 186000 人)进行。登记新发病例的条件是在研究期间根据现有分类标准确认明确诊断(2002 年 3 月 1 日至 2003 年 3 月 1 日)。患病率研究基于参与风湿病学家和其他专家的患者登记册中确定的既定诊断(2002 年 3 月 1 日之前)。使用欧洲标准人口计算发病率和患病率的年龄标准化估计值。

结果

16 岁及以上成年人 PsA 的总年发病率为 3.6/100000(95%置信区间[CI] 1.4-7.6/100000),PsA 的患病率为 49.1/100000(95%CI 39.5-60.4/100000)。成年人 AS 的年发病率为 6.4/100000(95%CI 3.3-11.3/100000),AS 的患病率为 94.2/100000(95%CI 80.8-109.2/100000)。成年人 ReA 的年发病率为 9.3/100000(95%CI 5.5-14.8/100000),ReA 的患病率为 91.3/100000(95%CI 78.1-106.2/100000)。

结论

捷克共和国首次基于人群的调查中 PsA、AS 和 ReA 的年发病率和患病率与其他国家报告的数据相当。

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