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1982 - 2001年希腊西北部银屑病关节炎的流行病学

Epidemiology of psoriatic arthritis in northwest Greece, 1982-2001.

作者信息

Alamanos Yannis, Papadopoulos Nikolaos G, Voulgari Paraskevi V, Siozos Christos, Psychos Dimitrios N, Tympanidou Maria, Drosos Alexandros A

机构信息

Department of Hygiene and Epidemiology, University of Ioannina Medical School, 451 10 Ioannina, Greece.

出版信息

J Rheumatol. 2003 Dec;30(12):2641-4.

PMID:14719208
Abstract

OBJECTIVE

To investigate the frequency and distribution of psoriatic arthritis (PsA) in a defined area of Northwest Greece, with a population of about 500,000 inhabitants.

METHODS

Cases were recorded from in- and outpatients referred to the Rheumatology Clinics of the Ioannina University Hospital and the Ioannina General Hospital, and from patients referred to private rheumatologists practicing in the study area. All patients recorded between January 1, 1982, and December 31, 2001, resident in the study area, were included. The study area included the Department of Epirus and the northern part of the Department of Ionian Islands. Diagnosis was based on the European Spondylarthropathy Study Group criteria. Incidence and prevalence rates were calculated as number of cases per 100,000 inhabitants. Population data were based on the National Census.

RESULTS

The age-adjusted prevalence of PsA was 56.6 cases per 100,000 adults on December 31, 2001. A total of 221 new cases were diagnosed during the study period, giving an age-adjusted mean incidence rate of 3.02 cases per 100,000 adults. There was no significant difference observed between men and women. The peak of incidence was observed in the age group 45-64 years. Incidence of diagnosed PsA increased during the study period.

CONCLUSION

The incidence and prevalence of PsA in Northwest Greece was roughly half that reported in studies from the US and Northern Europe. This frequency tended to increase in the last decade.

摘要

目的

调查希腊西北部一个约有50万居民的特定区域中银屑病关节炎(PsA)的发病率及分布情况。

方法

病例记录来自约阿尼纳大学医院和约阿尼纳综合医院风湿科门诊及住院患者,以及转诊至在研究区域执业的私人风湿病专家处的患者。纳入所有于1982年1月1日至2001年12月31日期间居住在研究区域的记录患者。研究区域包括伊庇鲁斯地区和爱奥尼亚群岛地区北部。诊断依据欧洲脊柱关节病研究组标准。发病率和患病率按每10万居民中的病例数计算。人口数据基于全国人口普查。

结果

2001年12月31日,PsA年龄调整后的患病率为每10万成年人中有56.6例。研究期间共诊断出221例新病例,年龄调整后的平均发病率为每10万成年人中有3.02例。未观察到男性和女性之间存在显著差异。发病率高峰出现在45 - 64岁年龄组。研究期间确诊的PsA发病率有所上升。

结论

希腊西北部PsA的发病率和患病率约为美国和北欧研究报告的一半。在过去十年中,这一发病率有上升趋势。

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