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New experimental and theoretical approaches towards the understanding of the emergence of viral infections. Introduction.

作者信息

Elena Santiago F, Froissart Rémy

机构信息

Instituto de Biología Molecular y Celular de Plantas, CSIC-UPV, 46022 Valencia, Spain.

出版信息

Philos Trans R Soc Lond B Biol Sci. 2010 Jun 27;365(1548):1867-9. doi: 10.1098/rstb.2010.0088.

Abstract
摘要

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Arabidopsis thaliana as a model for the study of plant-virus co-evolution.
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Mutational fitness effects in RNA and single-stranded DNA viruses: common patterns revealed by site-directed mutagenesis studies.
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HIV-1 evolution: frustrating therapies, but disclosing molecular mechanisms.
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Methods of modelling viral disease dynamics across the within- and between-host scales: the impact of virus dose on host population immunity.
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Combining mathematics and empirical data to predict emergence of RNA viruses that differ in reservoir use.
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The virulence-transmission trade-off in vector-borne plant viruses: a review of (non-)existing studies.
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Lifestyles of plant viruses.
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