Funder Kamilia S, Steinmetz Jacob, Rasmussen Lars S
Center of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Semin Cardiothorac Vasc Anesth. 2010 Jun;14(2):119-22. doi: 10.1177/1089253210371520.
Postoperative cognitive dysfunction (POCD) is a subtle impairment of memory, concentration, and speed of information processing. It is a frequent complication following surgery and can have a debilitating effect on patients' recovery and future prognosis. Neuropsychological testing is needed to reveal postoperative cognitive decline, and questionnaires are not useful for this purpose. There is a profound lack of consensus regarding the research methodology for detection of cognitive deterioration, especially the diagnostic criteria. Issues, such as baseline performance, learning effects, and the interval between test sessions, also influence test results and must be considered when designing and interpreting POCD data.
术后认知功能障碍（POCD）是一种记忆、注意力和信息处理速度的细微损害。它是手术后常见的并发症，会对患者的康复和未来预后产生不利影响。需要进行神经心理学测试来揭示术后认知能力下降，而问卷调查对此目的并无用处。在检测认知功能恶化的研究方法，尤其是诊断标准方面，存在严重的共识缺失。诸如基线表现、学习效应以及测试 sessions 之间的间隔等问题，也会影响测试结果，在设计和解释POCD数据时必须予以考虑。 （注：原文中“test sessions”可能表述有误，推测可能是“test sessions”，可根据实际情况调整准确翻译）
