Coelho Joana Dias, Afonso Ana, Feio Ana Barata
Dermatology Clinic Dr. Barata Feio, Lisbon, Portugal.
J Cosmet Laser Ther. 2010 Jun;12(3):155-6. doi: 10.3109/14764172.2010.487911.
Lymphomatoid papulosis (LyP) is a rare skin lymphoproliferative disorder that has been reported only rarely in children. It is included in the World Health Organization classification of cutaneous lymphomas. We report a case of LyP in a 13-year-old Caucasian girl who presented with a 6-month history of recurrent papular lesions on the left upper arm. Histopathologic examination showed a diffuse cellular infiltration of small and medium-sized T lymphocytes CD30+ in the superficial dermis. Treatment was started using a UVB phototherapy handpiece (twice weekly), with resolution of the lesions after 6 weeks of treatment. There was a relapse after 9 months with a good response after six more sessions of treatment. The patient is in good health without lesions after 12 months of follow-up.
淋巴瘤样丘疹病(LyP)是一种罕见的皮肤淋巴细胞增殖性疾病,在儿童中仅有极少病例报道。它被纳入世界卫生组织皮肤淋巴瘤分类中。我们报告一例13岁白种女孩患淋巴瘤样丘疹病的病例,该女孩左上臂反复出现丘疹性皮损6个月。组织病理学检查显示真皮浅层有弥漫性的中小T淋巴细胞CD30+细胞浸润。开始使用UVB光疗手持器进行治疗(每周两次),治疗6周后皮损消退。9个月后复发,再次进行6次治疗后反应良好。随访12个月时患者健康状况良好,无皮损。