Sebko T V, Aliev V A
Vestn Akad Med Nauk SSSR. 1991(2):46-50.
Fibronectin is a high-molecular polyfunctional glycoprotein occurring in the majority of the body fluids and tissues. Various investigations have demonstrated that plasma fibronectin levels either fail to change, or increase with longer gestation during a normal pregnancy. The time course of changes in fibronectin levels has been found to become lower in the amniotic fluid during pregnancy, though its physiological role has not been defined in this case. In late gestosis, plasma fibronectin concentrations substantially rises as compared to those observed in normal pregnancy.
纤连蛋白是一种高分子多功能糖蛋白，存在于大多数体液和组织中。各种研究表明，在正常妊娠期间，血浆纤连蛋白水平要么不变，要么随着妊娠期延长而升高。虽然在羊水的情况下其生理作用尚未明确，但已发现妊娠期间羊水中纤连蛋白水平的变化时间进程会降低。在晚期妊娠中毒症中，与正常妊娠相比，血浆纤连蛋白浓度大幅升高。
