Department of Pediatrics, Division of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Nicotine Tob Res. 2010 Jul;12(7):748-55. doi: 10.1093/ntr/ntq076. Epub 2010 May 19.
The purpose of this study was to examine whether (a) early pubertal timing effects on smoking onset existed for both White and Black girls and (b) whether the association between pubertal timing and smoking onset was moderated by race.
Participants included 264 girls (14.9 +/- 2.2 years, 164 White, and 100 Black) at the baseline report of a longitudinal study of whom 153 reported smoking and age at first cigarette.
Kaplan-Meier analysis stratified by racial group showed a significant difference between the pubertal timing groups for Black girls only. After accounting for covariates using Cox regression, there was no significant interaction between pubertal timing and racial group. There was a main effect of pubertal timing indicating that late maturers were at significantly lower risk for smoking initiation compared with the early and on-time groups, but the early and on-time groups were not significantly different from each other.
Results point to equal risk of early smoking onset for early and on-time maturers of both racial groups, indicating the need for smoking prevention in early adolescence for both White and Black females.
本研究旨在检验以下两点：（a）青春期提前是否会对白人女孩和黑人女孩的吸烟起始产生影响；（b）青春期提前与吸烟起始之间的关联是否会受到种族的调节。
参与者包括纵向研究的 264 名女孩（14.9 +/- 2.2 岁，164 名白人，100 名黑人），其中 153 名报告了吸烟情况和首次吸烟的年龄。
按种族分层的 Kaplan-Meier 分析显示，仅在黑人女孩中，青春期提前组之间存在显著差异。在用 Cox 回归控制协变量后，青春期提前与种族群体之间没有显著的交互作用。青春期提前有显著的主效应，表明晚熟者吸烟起始的风险显著低于早熟者和适时者，但早熟者和适时者之间没有显著差异。
结果表明，两个种族群体的早熟者和适时者的早期吸烟起始风险相等，这表明需要对白人女性和黑人女性进行青少年早期的吸烟预防。
