Centro de Investigación en Nanociencia y Nanotecnología (ICN-CSIC) Campus UAB, 08193 Bellaterra, Spain.
Chem Commun (Camb). 2010 Jul 14;46(26):4737-9. doi: 10.1039/c003084h. Epub 2010 May 20.
Micro- and nanoscale coordination polymer particles can be used for encapsulating and delivering drugs. In vitro cancer cell cytotoxicity assays showed that these capsules readily release doxorubicin, which shows anticancer efficacy. The results from this work open up new avenues for metal-organic capsules to be used as potential drug delivery systems.
微纳米级配位聚合物颗粒可用于包裹和输送药物。体外癌细胞细胞毒性试验表明,这些胶囊容易释放阿霉素,显示出抗癌功效。这项工作的结果为金属有机胶囊作为潜在药物输送系统的应用开辟了新途径。