Shefren G, Collin J, Soriero O
Department of Obstetrics and Gynecology, El Camino Hospital, Mountain View, CA.
Am J Obstet Gynecol. 1991 Jun;164(6 Pt 1):1617-20; discussion 1620-1. doi: 10.1016/0002-9378(91)91445-3.
Gliomatosis peritonei is the implantation of glial tissue within the peritoneal cavity associated with ovarian teratomas. Previous reports have emphasized improved outcomes when these implants are found to be mature, even if the ovarian component is immature. A 16-year-old female with grade 3 immature teratoma was found on two subsequent laparotomies to have extensive peritoneal implantation of mature glial tissue. More than 5 years after the original surgery she was found to have a malignant abdominal glial neoplasm. This case illustrates a rare finding of malignant transformation of previously mature gliomatosis peritonei.
腹膜胶质细胞瘤病是指与卵巢畸胎瘤相关的胶质组织在腹腔内种植。既往报道强调,即便卵巢成分不成熟,但如果这些种植灶为成熟型,则预后较好。一名16岁患有3级未成熟畸胎瘤的女性,在随后的两次剖腹手术中发现有广泛的成熟胶质组织腹膜种植。在初次手术后5年多,她被发现患有恶性腹部胶质肿瘤。该病例说明了先前成熟的腹膜胶质细胞瘤病发生恶性转化这一罕见情况。