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直肠手术后的性功能障碍:无疾病复发男性的回顾性研究。

Sexual dysfunction after rectal surgery: a retrospective study of men without disease recurrence.

机构信息

Department of Urology, Ansbach Medical Center, Ansbach, Germany.

出版信息

J Sex Med. 2010 Sep;7(9):3199-205. doi: 10.1111/j.1743-6109.2010.01846.x.

DOI:10.1111/j.1743-6109.2010.01846.x
PMID:20487235
Abstract

INTRODUCTION

Sexual dysfunction is a frequent complication of visceral surgery after rectal resections as a result of carcinoma of the rectum.

AIM

The purpose of our study is to assess the incidence and form of sexual dysfunction in our own population of patients.

METHODS

The study comprised all patients who had undergone surgery for carcinoma of the rectum at the Erlangen Surgery University Hospital, Germany, in the period 2000-04. All male patients were retrospectively surveyed and asked to complete standardized (International Index of Erectile Function 15) questionnaires regarding their pre- and postsurgical sexual function. One hundred and forty-five questionnaires could be analyzed. The statistical evaluation was conducted with aid of the SPSS statistics program. The univariate analysis was carried out with the chi-square test and the U-test (Mann-Whitney Test).

MAIN OUTCOME MEASURES

Erectile dysfunction, libido, and ability to have and sustain ejaculation and orgasm (both before and after surgery in each case) were among the dependent variables when compiling the data. The impact various surgical procedures and radiochemotherapy had on the severity of the sexual dysfunctions was analyzed. The scope of the postoperative urological care given was also assessed.

RESULTS

Erectile dysfunction was confirmed in N=112 patients (77.3%) after surgery (P-value<0.001). Other parameters such as orgasm capacity (4.1% vs. 16.5%), ejaculation ability (1.4% vs. 12.4%) and libido (3.4% vs. 22%) also showed a marked deterioration postoperatively. Postoperative erectile dysfunction was present in 77% of the patients with a colostomy and in 88.5% of the patients who had received neoadjuvant radiation.

CONCLUSIONS

Male erectile dysfunction is a frequent complication after rectal resection as a result of carcinoma of the rectum. The high incidence of sexual dysfunctions results from the radical nature of the procedure and from additional radiation or colostomy therapy. These patients need accompanying urological care for treatment of their sexual dysfunction.

摘要

引言

直肠切除术治疗直肠癌后,常并发内脏手术相关的性功能障碍。

目的

评估我们自己的患者人群中性功能障碍的发生率和类型。

方法

本研究纳入了 2000 年 4 月期间在德国埃尔兰根外科大学医院接受直肠癌手术的所有患者。回顾性调查所有男性患者,并要求他们填写标准化(国际勃起功能指数 15 项)问卷,以评估他们手术前后的性功能。共分析了 145 份问卷。使用 SPSS 统计程序进行统计评估。单变量分析采用卡方检验和 U 检验(Mann-Whitney 检验)。

主要观察指标

勃起功能障碍、性欲以及射精和性高潮的能力(每种情况均为手术前后)是数据编译中的因变量。分析了各种手术程序和放化疗对性功能障碍严重程度的影响。还评估了术后泌尿科护理的范围。

结果

手术后 112 例(77.3%)患者确诊为勃起功能障碍(P 值<0.001)。其他参数,如性高潮能力(4.1%比 16.5%)、射精能力(1.4%比 12.4%)和性欲(3.4%比 22%)也显示出明显的术后恶化。造口术和新辅助放疗患者的术后勃起功能障碍分别为 77%和 88.5%。

结论

直肠癌直肠切除术后男性勃起功能障碍是一种常见的并发症。性功能障碍的高发率是手术的根治性和额外的放疗或造口术治疗导致的。这些患者需要伴随泌尿科治疗来治疗他们的性功能障碍。

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